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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC27 All Species: 31.52
Human Site: S65 Identified Species: 57.78
UniProt: P30260 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30260 NP_001107563.1 824 91867 S65 Y R L L K G H S C T T P Q C K
Chimpanzee Pan troglodytes XP_511624 824 91839 S65 Y R L L K G H S C T T P Q C K
Rhesus Macaque Macaca mulatta XP_001115994 824 91959 S65 Y R L L K G H S C T T P Q C K
Dog Lupus familis XP_548047 825 91842 S65 Y R L L K G H S C T T P Q C K
Cat Felis silvestris
Mouse Mus musculus NP_663411 825 91824 S65 Y R L L K G H S C T T P Q C K
Rat Rattus norvegicus NP_001019964 824 91645 S65 Y R L L K G H S C T T P Q C K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520967 385 43892
Chicken Gallus gallus NP_001006331 833 92606 S65 Y R L L K G H S C T T P Q C K
Frog Xenopus laevis NP_001085568 833 92363 S65 Y R L L K A H S C T T P Q C K
Zebra Danio Brachydanio rerio NP_958857 790 87878 H64 A Y H L L K R H S C T T P Q C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648093 900 101266 A64 Y W L L K E K A R R S P Q C R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786824 824 91473 R63 G C P T P D C R F L M A R C C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38042 758 85418 D32 S T I I Q L Q D C I Q Q A I Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 96.3 99.1 N.A. 96.9 97.4 N.A. 43.6 94.5 89.6 76.5 N.A. 39.2 N.A. N.A. 49.2
Protein Similarity: 100 99.8 97.2 99.2 N.A. 98.6 98.5 N.A. 45.2 96.6 94.5 84.3 N.A. 57.4 N.A. N.A. 67.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 100 93.3 13.3 N.A. 46.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 93.3 13.3 N.A. 66.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 0 8 0 0 0 8 8 0 0 % A
% Cys: 0 8 0 0 0 0 8 0 70 8 0 0 0 77 16 % C
% Asp: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 54 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 62 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 8 0 0 0 8 0 % I
% Lys: 0 0 0 0 70 8 8 0 0 0 0 0 0 0 62 % K
% Leu: 0 0 70 77 8 8 0 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 8 0 0 0 0 0 0 70 8 0 0 % P
% Gln: 0 0 0 0 8 0 8 0 0 0 8 8 70 8 8 % Q
% Arg: 0 62 0 0 0 0 8 8 8 8 0 0 8 0 8 % R
% Ser: 8 0 0 0 0 0 0 62 8 0 8 0 0 0 0 % S
% Thr: 0 8 0 8 0 0 0 0 0 62 70 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 70 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _