Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WEE1 All Species: 11.52
Human Site: S211 Identified Species: 19.49
UniProt: P30291 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30291 NP_003381.1 646 71597 S211 S S V K L R G S S L F M D T E
Chimpanzee Pan troglodytes XP_521839 646 71607 S211 S S V K L R G S S L F M D T E
Rhesus Macaque Macaca mulatta NP_001099016 568 63102 L166 T P E S Y R K L F L Q S G G K
Dog Lupus familis XP_534051 887 95991 G452 S S V K L R G G S L F M D T E
Cat Felis silvestris
Mouse Mus musculus P47810 646 71560 G210 S G S V K L R G S S L F M D T
Rat Rattus norvegicus Q63802 646 71478 S211 S S V K L R G S S L F M D T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510171 572 63943 L170 F T P D S M L L H S S G Q C R
Chicken Gallus gallus NP_001026352 641 70947 L207 V K L R G G S L F M N V G R S
Frog Xenopus laevis P47817 555 61670 E152 N I N P F T P E S Y R Q T H F
Zebra Danio Brachydanio rerio NP_001005770 612 68517 N198 R N Q T P R V N I N P F T P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54350 609 68790 S199 A M Q K Y L L S D A C D D D V
Honey Bee Apis mellifera XP_624069 589 66032 R187 R K R T R S K R S L N G S P D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999796 624 68925 S206 M R N L Q R R S T R I P K T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L4H0 500 56512 F98 D F I L S Q D F F C T P D Y I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 42.1 70.9 N.A. 90.5 91.6 N.A. 72.7 80.1 42.8 64.2 N.A. 36.5 41.6 N.A. 39.6
Protein Similarity: 100 99.8 56.1 71.3 N.A. 92.7 93.1 N.A. 79.2 85.9 55.2 75 N.A. 54.1 59.2 N.A. 55.5
P-Site Identity: 100 100 13.3 93.3 N.A. 13.3 100 N.A. 0 0 6.6 6.6 N.A. 20 13.3 N.A. 20
P-Site Similarity: 100 100 26.6 93.3 N.A. 13.3 100 N.A. 6.6 26.6 13.3 26.6 N.A. 26.6 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % C
% Asp: 8 0 0 8 0 0 8 0 8 0 0 8 43 15 15 % D
% Glu: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 29 % E
% Phe: 8 8 0 0 8 0 0 8 22 0 29 15 0 0 8 % F
% Gly: 0 8 0 0 8 8 29 15 0 0 0 15 15 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % H
% Ile: 0 8 8 0 0 0 0 0 8 0 8 0 0 0 8 % I
% Lys: 0 15 0 36 8 0 15 0 0 0 0 0 8 0 8 % K
% Leu: 0 0 8 15 29 15 15 22 0 43 8 0 0 0 0 % L
% Met: 8 8 0 0 0 8 0 0 0 8 0 29 8 0 0 % M
% Asn: 8 8 15 0 0 0 0 8 0 8 15 0 0 0 0 % N
% Pro: 0 8 8 8 8 0 8 0 0 0 8 15 0 15 0 % P
% Gln: 0 0 15 0 8 8 0 0 0 0 8 8 8 0 0 % Q
% Arg: 15 8 8 8 8 50 15 8 0 8 8 0 0 8 15 % R
% Ser: 36 29 8 8 15 8 8 36 50 15 8 8 8 0 8 % S
% Thr: 8 8 0 15 0 8 0 0 8 0 8 0 15 36 8 % T
% Val: 8 0 29 8 0 0 8 0 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 0 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _