KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE1
All Species:
18.18
Human Site:
S389
Identified Species:
30.77
UniProt:
P30291
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30291
NP_003381.1
646
71597
S389
G
S
L
A
D
A
I
S
E
N
Y
R
I
M
S
Chimpanzee
Pan troglodytes
XP_521839
646
71607
S389
G
S
L
A
D
A
I
S
E
N
Y
R
I
M
S
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
S344
V
H
L
D
I
K
P
S
N
I
F
I
C
H
K
Dog
Lupus familis
XP_534051
887
95991
S630
G
S
L
A
D
A
I
S
E
N
Y
R
S
M
S
Cat
Felis silvestris
Mouse
Mus musculus
P47810
646
71560
S388
G
S
L
A
D
A
I
S
E
N
Y
R
V
M
S
Rat
Rattus norvegicus
Q63802
646
71478
E389
S
L
A
D
A
V
S
E
N
Y
R
V
M
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510171
572
63943
L348
R
Y
I
H
S
M
S
L
V
H
M
D
I
K
P
Chicken
Gallus gallus
NP_001026352
641
70947
S385
G
S
L
A
D
A
I
S
E
N
Y
R
N
M
R
Frog
Xenopus laevis
P47817
555
61670
G330
M
G
L
K
Y
I
H
G
S
G
L
V
H
M
D
Zebra Danio
Brachydanio rerio
NP_001005770
612
68517
V376
L
K
D
L
L
L
Q
V
S
R
G
L
K
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
K377
T
M
N
P
N
A
H
K
L
V
E
V
Q
P
Q
Honey Bee
Apis mellifera
XP_624069
589
66032
N365
H
M
D
I
K
P
G
N
I
F
I
S
K
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
L384
H
R
M
T
E
I
E
L
K
Q
V
L
V
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L4H0
500
56512
A276
R
M
D
G
C
L
Y
A
V
K
H
S
T
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
42.1
70.9
N.A.
90.5
91.6
N.A.
72.7
80.1
42.8
64.2
N.A.
36.5
41.6
N.A.
39.6
Protein Similarity:
100
99.8
56.1
71.3
N.A.
92.7
93.1
N.A.
79.2
85.9
55.2
75
N.A.
54.1
59.2
N.A.
55.5
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
0
N.A.
6.6
86.6
13.3
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
20
93.3
N.A.
100
6.6
N.A.
20
86.6
13.3
0
N.A.
13.3
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
36
8
43
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
22
15
36
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
0
8
0
8
8
36
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
36
8
0
8
0
0
8
8
0
8
8
0
0
0
0
% G
% His:
15
8
0
8
0
0
15
0
0
8
8
0
8
8
0
% H
% Ile:
0
0
8
8
8
15
36
0
8
8
8
8
22
0
15
% I
% Lys:
0
8
0
8
8
8
0
8
8
8
0
0
15
8
22
% K
% Leu:
8
8
50
8
8
15
0
15
8
0
8
15
0
0
0
% L
% Met:
8
22
8
0
0
8
0
0
0
0
8
0
8
43
0
% M
% Asn:
0
0
8
0
8
0
0
8
15
36
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
8
8
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
0
0
8
8
8
% Q
% Arg:
15
8
0
0
0
0
0
0
0
8
8
36
0
8
8
% R
% Ser:
8
36
0
0
8
0
15
43
15
0
0
15
8
8
29
% S
% Thr:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
0
0
8
0
8
15
8
8
22
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
8
0
0
8
36
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _