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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE1
All Species:
27.88
Human Site:
S571
Identified Species:
47.18
UniProt:
P30291
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30291
NP_003381.1
646
71597
S571
V
K
H
S
V
L
L
S
A
S
R
K
S
A
E
Chimpanzee
Pan troglodytes
XP_521839
646
71607
S571
V
K
H
S
V
L
L
S
A
S
R
K
S
A
E
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
L503
E
L
Q
Q
Q
L
N
L
E
K
F
K
T
A
T
Dog
Lupus familis
XP_534051
887
95991
S812
V
K
H
S
V
L
L
S
A
S
R
K
S
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P47810
646
71560
S570
V
K
H
S
V
L
L
S
A
S
R
K
S
A
E
Rat
Rattus norvegicus
Q63802
646
71478
S570
V
K
H
S
V
L
L
S
A
S
R
K
S
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510171
572
63943
R507
R
K
S
A
E
Q
L
R
I
E
L
N
A
E
K
Chicken
Gallus gallus
NP_001026352
641
70947
S567
V
K
H
S
V
L
L
S
A
A
K
K
S
A
E
Frog
Xenopus laevis
P47817
555
61670
Q489
R
C
V
G
K
A
A
Q
L
Q
K
Q
L
N
V
Zebra Danio
Brachydanio rerio
NP_001005770
612
68517
T536
V
R
H
P
V
L
L
T
A
S
R
M
S
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
N544
R
K
N
E
I
L
M
N
K
L
R
E
A
K
K
Honey Bee
Apis mellifera
XP_624069
589
66032
A524
Q
L
R
R
E
L
N
A
E
K
L
K
N
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
D544
L
Q
T
M
I
D
P
D
P
S
Q
R
P
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L4H0
500
56512
Y435
F
S
L
G
V
T
V
Y
E
L
I
K
G
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
42.1
70.9
N.A.
90.5
91.6
N.A.
72.7
80.1
42.8
64.2
N.A.
36.5
41.6
N.A.
39.6
Protein Similarity:
100
99.8
56.1
71.3
N.A.
92.7
93.1
N.A.
79.2
85.9
55.2
75
N.A.
54.1
59.2
N.A.
55.5
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
13.3
86.6
0
66.6
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
33.3
100
13.3
86.6
N.A.
66.6
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
8
50
8
0
0
15
58
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% D
% Glu:
8
0
0
8
15
0
0
0
22
8
0
8
0
15
43
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
58
0
0
8
0
0
0
8
15
15
65
0
8
15
% K
% Leu:
8
15
8
0
0
72
58
8
8
15
15
0
8
0
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
15
8
0
0
0
8
8
8
0
% N
% Pro:
0
0
0
8
0
0
8
0
8
0
0
0
8
0
8
% P
% Gln:
8
8
8
8
8
8
0
8
0
8
8
8
0
0
0
% Q
% Arg:
22
8
8
8
0
0
0
8
0
0
50
8
0
0
0
% R
% Ser:
0
8
8
43
0
0
0
43
0
50
0
0
50
15
0
% S
% Thr:
0
0
8
0
0
8
0
8
0
0
0
0
8
0
8
% T
% Val:
50
0
8
0
58
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _