Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIP All Species: 7.27
Human Site: S245 Identified Species: 13.33
UniProt: P30301 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30301 NP_036196.1 263 28122 S245 K G A K P D V S N G Q P E V T
Chimpanzee Pan troglodytes XP_001157396 268 28320 E245 E P D T D W E E R E V R R R Q
Rhesus Macaque Macaca mulatta XP_001115118 263 28173 A245 R G V K P E D A N G Q P E V T
Dog Lupus familis XP_543678 271 28842 D245 K G L E P D A D W E E R E V R
Cat Felis silvestris
Mouse Mus musculus P51180 263 28174 S245 K G A R P S D S N G Q P E G T
Rat Rattus norvegicus P09011 261 27873 S243 K G A R P S D S N G Q P E G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507447 264 27892 P245 R G D R P S A P E G P G E A L
Chicken Gallus gallus P28238 262 27053 A245 R G E P P A A A P P P E P P A
Frog Xenopus laevis NP_001088304 264 28636 P246 K G A R P A V P E G Q R E T A
Zebra Danio Brachydanio rerio NP_001003534 263 28765 P245 K G N K P T E P E A Q Q E T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V5Z7 245 25557 R228 L L A G I I Y R L I F K V R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9AT75 266 27377 I248 L V Y E Y L L I P P A D A V P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q41951 250 25009 G233 G L A G L I Y G N V F M G S S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.7 97.3 61.6 N.A. 93.1 92.7 N.A. 79.1 63.1 76.5 70.3 N.A. 38.7 N.A. N.A. N.A.
Protein Similarity: 100 73.1 98.4 78.2 N.A. 96.9 96.1 N.A. 88.2 78.3 88.6 83.6 N.A. 55.8 N.A. N.A. N.A.
P-Site Identity: 100 0 66.6 40 N.A. 73.3 73.3 N.A. 26.6 13.3 53.3 40 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 86.6 53.3 N.A. 80 80 N.A. 40 26.6 60 40 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 39.8 N.A. 35.3 N.A. N.A.
Protein Similarity: N.A. 54.1 N.A. 52 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 47 0 0 16 24 16 0 8 8 0 8 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 8 16 24 8 0 0 0 8 0 0 0 % D
% Glu: 8 0 8 16 0 8 16 8 24 16 8 8 62 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % F
% Gly: 8 70 0 16 0 0 0 8 0 47 0 8 8 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 16 0 8 0 8 0 0 0 0 0 % I
% Lys: 47 0 0 24 0 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 16 16 8 0 8 8 8 0 8 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 39 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 70 0 0 24 16 16 16 31 8 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 47 8 0 0 8 % Q
% Arg: 24 0 0 31 0 0 0 8 8 0 0 24 8 16 16 % R
% Ser: 0 0 0 0 0 24 0 24 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 8 0 8 0 0 0 0 0 0 0 16 31 % T
% Val: 0 8 8 0 0 0 16 0 0 8 8 0 8 31 0 % V
% Trp: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 16 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _