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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIP
All Species:
13.33
Human Site:
T252
Identified Species:
24.44
UniProt:
P30301
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30301
NP_036196.1
263
28122
T252
S
N
G
Q
P
E
V
T
G
E
P
V
E
L
N
Chimpanzee
Pan troglodytes
XP_001157396
268
28320
Q252
E
R
E
V
R
R
R
Q
S
V
E
L
H
S
P
Rhesus Macaque
Macaca mulatta
XP_001115118
263
28173
T252
A
N
G
Q
P
E
V
T
G
E
P
V
E
L
N
Dog
Lupus familis
XP_543678
271
28842
R252
D
W
E
E
R
E
V
R
R
R
Q
S
V
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P51180
263
28174
T252
S
N
G
Q
P
E
G
T
G
E
P
V
E
L
K
Rat
Rattus norvegicus
P09011
261
27873
T250
S
N
G
Q
P
E
G
T
G
E
P
V
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507447
264
27892
L252
P
E
G
P
G
E
A
L
S
G
D
P
V
E
L
Chicken
Gallus gallus
P28238
262
27053
A252
A
P
P
P
E
P
P
A
E
P
L
E
L
K
T
Frog
Xenopus laevis
NP_001088304
264
28636
A253
P
E
G
Q
R
E
T
A
G
D
P
I
E
L
K
Zebra Danio
Brachydanio rerio
NP_001003534
263
28765
R252
P
E
A
Q
Q
E
T
R
G
E
P
I
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
K235
R
L
I
F
K
V
R
K
G
D
D
E
T
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9AT75
266
27377
P255
I
P
P
A
D
A
V
P
H
T
H
Q
P
L
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q41951
250
25009
S240
G
N
V
F
M
G
S
S
E
H
V
P
L
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.7
97.3
61.6
N.A.
93.1
92.7
N.A.
79.1
63.1
76.5
70.3
N.A.
38.7
N.A.
N.A.
N.A.
Protein Similarity:
100
73.1
98.4
78.2
N.A.
96.9
96.1
N.A.
88.2
78.3
88.6
83.6
N.A.
55.8
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
13.3
N.A.
86.6
86.6
N.A.
13.3
0
46.6
46.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
20
N.A.
86.6
86.6
N.A.
13.3
6.6
60
53.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.8
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
54.1
N.A.
52
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
8
0
8
8
16
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
16
16
0
0
8
0
% D
% Glu:
8
24
16
8
8
62
0
0
16
39
8
16
47
16
0
% E
% Phe:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
47
0
8
8
16
0
54
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
8
0
8
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
16
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
31
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
8
8
16
54
16
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
16
% N
% Pro:
24
16
16
16
31
8
8
8
0
8
47
16
8
0
8
% P
% Gln:
0
0
0
47
8
0
0
8
0
0
8
8
0
0
0
% Q
% Arg:
8
8
0
0
24
8
16
16
8
8
0
0
0
0
0
% R
% Ser:
24
0
0
0
0
0
8
8
16
0
0
8
0
8
16
% S
% Thr:
0
0
0
0
0
0
16
31
0
8
0
0
8
0
8
% T
% Val:
0
0
8
8
0
8
31
0
0
8
8
31
16
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _