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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIP
All Species:
25.76
Human Site:
Y178
Identified Species:
47.22
UniProt:
P30301
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30301
NP_036196.1
263
28122
Y178
G
H
L
F
G
M
Y
Y
T
G
A
G
M
N
P
Chimpanzee
Pan troglodytes
XP_001157396
268
28320
W178
G
H
L
L
G
V
A
W
D
G
G
S
A
A
V
Rhesus Macaque
Macaca mulatta
XP_001115118
263
28173
Y178
G
H
L
F
G
M
Y
Y
T
G
A
G
M
N
P
Dog
Lupus familis
XP_543678
271
28842
Y178
G
H
L
L
G
I
H
Y
T
G
C
S
M
N
P
Cat
Felis silvestris
Mouse
Mus musculus
P51180
263
28174
Y178
G
H
L
F
G
M
Y
Y
T
G
A
G
M
N
P
Rat
Rattus norvegicus
P09011
261
27873
Y176
G
H
L
F
G
M
Y
Y
T
G
A
G
M
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507447
264
27892
C178
G
H
L
F
G
M
Y
C
T
G
A
G
M
N
P
Chicken
Gallus gallus
P28238
262
27053
F178
G
H
L
F
G
I
P
F
T
G
A
G
M
N
P
Frog
Xenopus laevis
NP_001088304
264
28636
Y179
G
H
L
F
G
I
Y
Y
T
G
A
S
M
N
P
Zebra Danio
Brachydanio rerio
NP_001003534
263
28765
Y178
G
H
L
L
G
M
Y
Y
T
G
A
G
M
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
R161
K
A
V
S
D
P
G
R
Q
D
I
K
G
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9AT75
266
27377
G181
D
P
K
R
G
H
L
G
T
I
A
P
L
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q41951
250
25009
K166
A
T
A
A
D
P
K
K
G
S
L
G
T
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.7
97.3
61.6
N.A.
93.1
92.7
N.A.
79.1
63.1
76.5
70.3
N.A.
38.7
N.A.
N.A.
N.A.
Protein Similarity:
100
73.1
98.4
78.2
N.A.
96.9
96.1
N.A.
88.2
78.3
88.6
83.6
N.A.
55.8
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
66.6
N.A.
100
100
N.A.
93.3
80
86.6
93.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
80
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.8
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
54.1
N.A.
52
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
8
0
0
0
70
0
8
16
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
54
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
77
0
0
0
85
0
8
8
8
77
8
62
8
0
0
% G
% His:
0
77
0
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
24
0
0
0
8
8
0
0
8
0
% I
% Lys:
8
0
8
0
0
0
8
8
0
0
0
8
0
0
0
% K
% Leu:
0
0
77
24
0
0
8
0
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
47
0
0
0
0
0
0
70
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% N
% Pro:
0
8
0
0
0
16
8
0
0
0
0
8
0
0
70
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
8
0
24
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
77
0
0
0
8
0
0
% T
% Val:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
54
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _