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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIF All Species: 40
Human Site: S186 Identified Species: 62.86
UniProt: P30405 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30405 NP_005720.1 207 22040 S186 D V V K K I E S F G S K S G R
Chimpanzee Pan troglodytes XP_507866 207 22006 S186 D V V K K I E S F G S K S G R
Rhesus Macaque Macaca mulatta XP_001090367 207 21931 S186 D V V K K I E S F G S K S G K
Dog Lupus familis XP_853114 152 16516 S131 D V V K K I E S F G S R S G K
Cat Felis silvestris
Mouse Mus musculus Q99KR7 206 21718 S185 D V V K K I E S F G S K S G K
Rat Rattus norvegicus P29117 206 21791 S185 D V V K K I E S F G S K S G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505585 259 26645 S238 D V V K K I E S F G S K S G K
Chicken Gallus gallus NP_001026397 204 21688 S183 D V V K K I E S F G S K N G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032199 192 20761 A171 D V V R K V E A L G S R S G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 S207 D V V K K I E S Y G S Q S G K
Honey Bee Apis mellifera XP_393381 209 22791 A189 D V V R K L E A M G S Q S G K
Nematode Worm Caenorhab. elegans P52009 192 20692 K169 S V V K K I E K M G S R S G A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330 V152 V V K A I E K V G T R N G S T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38900 173 18473 V153 V V R D I E K V G S D S G R T
Baker's Yeast Sacchar. cerevisiae P14832 162 17372 S142 D I V K K V E S L G S P S G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97 69 N.A. 89.8 89.3 N.A. 65.2 81.6 N.A. 68.1 N.A. 61.2 66.5 59.9 N.A.
Protein Similarity: 100 100 99 72.4 N.A. 93.2 92.2 N.A. 69.5 85.5 N.A. 78.2 N.A. 72.6 77 68.1 N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 93.3 86.6 N.A. 66.6 N.A. 80 60 66.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 N.A. 100 93.3 73.3 N.A.
Percent
Protein Identity: N.A. 50.7 N.A. 51.2 55 N.A.
Protein Similarity: N.A. 59.9 N.A. 61.3 62.3 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 66.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 14 0 0 0 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 80 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 14 87 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 14 87 0 0 14 87 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 14 67 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 74 87 0 14 7 0 0 0 47 0 0 54 % K
% Leu: 0 0 0 0 0 7 0 0 14 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % Q
% Arg: 0 0 7 14 0 0 0 0 0 0 7 20 0 7 20 % R
% Ser: 7 0 0 0 0 0 0 67 0 7 87 7 80 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 14 % T
% Val: 14 94 87 0 0 14 0 14 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _