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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIF All Species: 14.55
Human Site: S31 Identified Species: 22.86
UniProt: P30405 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30405 NP_005720.1 207 22040 S31 L P A A R A C S K G S G D P S
Chimpanzee Pan troglodytes XP_507866 207 22006 S31 L P A A R A C S K G A G D P S
Rhesus Macaque Macaca mulatta XP_001090367 207 21931 S31 L P A A R A C S K G A G D P S
Dog Lupus familis XP_853114 152 16516
Cat Felis silvestris
Mouse Mus musculus Q99KR7 206 21718 S31 L S A T R T C S D G G A R G A
Rat Rattus norvegicus P29117 206 21791 S31 L S T T R T C S D G G A R G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505585 259 26645 G83 V P F R V P A G P G R G S C S
Chicken Gallus gallus NP_001026397 204 21688 S34 A A G A R G C S S D G A G P R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032199 192 20761 P31 G A Q A N N N P V V F F D I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 Q52 G Q L Q F G I Q I V R E Y S K
Honey Bee Apis mellifera XP_393381 209 22791 V36 R S S F A L L V R S F A V I A
Nematode Worm Caenorhab. elegans P52009 192 20692 G31 V F F D V S I G E E P A G R V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330 A17 M T V G G A P A G R I V M E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38900 173 18473 A18 M T V G G K S A G R I V M E L
Baker's Yeast Sacchar. cerevisiae P14832 162 17372
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97 69 N.A. 89.8 89.3 N.A. 65.2 81.6 N.A. 68.1 N.A. 61.2 66.5 59.9 N.A.
Protein Similarity: 100 100 99 72.4 N.A. 93.2 92.2 N.A. 69.5 85.5 N.A. 78.2 N.A. 72.6 77 68.1 N.A.
P-Site Identity: 100 93.3 93.3 0 N.A. 40 33.3 N.A. 26.6 33.3 N.A. 13.3 N.A. 0 0 0 N.A.
P-Site Similarity: 100 100 100 0 N.A. 46.6 40 N.A. 33.3 33.3 N.A. 20 N.A. 0 20 20 N.A.
Percent
Protein Identity: N.A. 50.7 N.A. 51.2 55 N.A.
Protein Similarity: N.A. 59.9 N.A. 61.3 62.3 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 0 N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 27 34 7 27 7 14 0 0 14 34 0 0 27 % A
% Cys: 0 0 0 0 0 0 40 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 7 0 0 0 0 14 7 0 0 27 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 7 0 7 0 14 0 % E
% Phe: 0 7 14 7 7 0 0 0 0 0 14 7 0 0 0 % F
% Gly: 14 0 7 14 14 14 0 14 14 40 20 27 14 14 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 14 0 7 0 14 0 0 14 0 % I
% Lys: 0 0 0 0 0 7 0 0 20 0 0 0 0 0 7 % K
% Leu: 34 0 7 0 0 7 7 0 0 0 0 0 0 0 14 % L
% Met: 14 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % M
% Asn: 0 0 0 0 7 7 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 27 0 0 0 7 7 7 7 0 7 0 0 27 0 % P
% Gln: 0 7 7 7 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 7 40 0 0 0 7 14 14 0 14 7 7 % R
% Ser: 0 20 7 0 0 7 7 40 7 7 7 0 7 7 27 % S
% Thr: 0 14 7 14 0 14 0 0 0 0 0 0 0 0 0 % T
% Val: 14 0 14 0 14 0 0 7 7 14 0 14 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _