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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIF All Species: 13.33
Human Site: S43 Identified Species: 20.95
UniProt: P30405 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30405 NP_005720.1 207 22040 S43 D P S S S S S S G N P L V Y L
Chimpanzee Pan troglodytes XP_507866 207 22006 S43 D P S S S S S S G N P L V Y L
Rhesus Macaque Macaca mulatta XP_001090367 207 21931 S43 D P S S S S S S G N P L V Y L
Dog Lupus familis XP_853114 152 16516 Y8 M N W A L C C Y L Q L K A D V
Cat Felis silvestris
Mouse Mus musculus Q99KR7 206 21718 G43 R G A N S S S G N P L V Y L D
Rat Rattus norvegicus P29117 206 21791 Q43 R G A N S S S Q N P L V Y L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505585 259 26645 R95 S C S P P A A R P N P R V Y L
Chicken Gallus gallus NP_001026397 204 21688 Y46 G P R N P L V Y L D V G A D N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032199 192 20761 P43 D I A A D N Q P L G R V T F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 S64 Y S K A S K M S T L P R V F F
Honey Bee Apis mellifera XP_393381 209 22791 L48 V I A E E M G L P R V F F D M
Nematode Worm Caenorhab. elegans P52009 192 20692 F43 G R V T M E L F N D V V P K T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330 V29 M E L Y A N E V P K T A E N F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38900 173 18473 T30 M E L Y A D T T P E T A E N F
Baker's Yeast Sacchar. cerevisiae P14832 162 17372 V19 G Q P I G R V V F K L Y N D I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97 69 N.A. 89.8 89.3 N.A. 65.2 81.6 N.A. 68.1 N.A. 61.2 66.5 59.9 N.A.
Protein Similarity: 100 100 99 72.4 N.A. 93.2 92.2 N.A. 69.5 85.5 N.A. 78.2 N.A. 72.6 77 68.1 N.A.
P-Site Identity: 100 100 100 0 N.A. 20 20 N.A. 40 6.6 N.A. 6.6 N.A. 26.6 0 0 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 40 40 N.A. 53.3 20 N.A. 40 N.A. 40 13.3 20 N.A.
Percent
Protein Identity: N.A. 50.7 N.A. 51.2 55 N.A.
Protein Similarity: N.A. 59.9 N.A. 61.3 62.3 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 27 20 14 7 7 0 0 0 0 14 14 0 0 % A
% Cys: 0 7 0 0 0 7 7 0 0 0 0 0 0 0 0 % C
% Asp: 27 0 0 0 7 7 0 0 0 14 0 0 0 27 14 % D
% Glu: 0 14 0 7 7 7 7 0 0 7 0 0 14 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 7 0 0 7 7 14 20 % F
% Gly: 20 14 0 0 7 0 7 7 20 7 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 14 0 7 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 7 0 0 7 0 0 0 14 0 7 0 7 0 % K
% Leu: 0 0 14 0 7 7 7 7 20 7 27 20 0 14 27 % L
% Met: 20 0 0 0 7 7 7 0 0 0 0 0 0 0 7 % M
% Asn: 0 7 0 20 0 14 0 0 20 27 0 0 7 14 7 % N
% Pro: 0 27 7 7 14 0 0 7 27 14 34 0 7 0 0 % P
% Gln: 0 7 0 0 0 0 7 7 0 7 0 0 0 0 0 % Q
% Arg: 14 7 7 0 0 7 0 7 0 7 7 14 0 0 0 % R
% Ser: 7 7 27 20 40 34 34 27 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 7 0 0 7 7 7 0 14 0 7 0 7 % T
% Val: 7 0 7 0 0 0 14 14 0 0 20 27 34 0 7 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 14 0 0 0 14 0 0 0 7 14 27 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _