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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TM4SF1 All Species: 20.3
Human Site: T143 Identified Species: 49.63
UniProt: P30408 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30408 NP_055035.1 202 21632 T143 E G Q Y L L D T S T W S E C T
Chimpanzee Pan troglodytes XP_516815 202 21724 T143 E G Q Y L L D T S T W S K C T
Rhesus Macaque Macaca mulatta XP_001108758 202 21708 T143 E G Q Y L L D T S T W S Q C T
Dog Lupus familis XP_542831 322 34385 T263 D G Q Y L L D T S T W S Q C V
Cat Felis silvestris
Mouse Mus musculus Q64302 202 22225 S143 E G Q Y L L N S S M W S K C Y
Rat Rattus norvegicus Q9EQL5 202 21466 Q140 D G D Y L N D Q A L W S K C E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507468 202 21691 H143 N G N Y L M D H S S W G N C L
Chicken Gallus gallus XP_422848 203 21955 Y144 S G G Y L L E Y N E W S K C Q
Frog Xenopus laevis NP_001087352 203 21675 H142 N G Q Y L T N H Q S W S T C S
Zebra Danio Brachydanio rerio NP_001003489 198 20755 R142 D G N Y L S N R T M W E L C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 98 47.2 N.A. 78.2 50 N.A. 83.6 64 71.9 46.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98 98.5 55.5 N.A. 90 68.8 N.A. 92 79.8 85.2 66.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 80 N.A. 66.6 46.6 N.A. 46.6 46.6 46.6 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 66.6 N.A. 60 66.6 66.6 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % C
% Asp: 30 0 10 0 0 0 60 0 0 0 0 0 0 0 0 % D
% Glu: 40 0 0 0 0 0 10 0 0 10 0 10 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 100 10 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % K
% Leu: 0 0 0 0 100 60 0 0 0 10 0 0 10 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 20 0 0 0 0 0 % M
% Asn: 20 0 20 0 0 10 30 0 10 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 60 0 0 0 0 10 10 0 0 0 20 0 10 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 10 0 10 60 20 0 80 0 0 10 % S
% Thr: 0 0 0 0 0 10 0 40 10 40 0 0 10 0 30 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % W
% Tyr: 0 0 0 100 0 0 0 10 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _