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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM4SF1
All Species:
19.7
Human Site:
T145
Identified Species:
48.15
UniProt:
P30408
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30408
NP_055035.1
202
21632
T145
Q
Y
L
L
D
T
S
T
W
S
E
C
T
E
P
Chimpanzee
Pan troglodytes
XP_516815
202
21724
T145
Q
Y
L
L
D
T
S
T
W
S
K
C
T
E
P
Rhesus Macaque
Macaca mulatta
XP_001108758
202
21708
T145
Q
Y
L
L
D
T
S
T
W
S
Q
C
T
E
P
Dog
Lupus familis
XP_542831
322
34385
T265
Q
Y
L
L
D
T
S
T
W
S
Q
C
V
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64302
202
22225
M145
Q
Y
L
L
N
S
S
M
W
S
K
C
Y
E
P
Rat
Rattus norvegicus
Q9EQL5
202
21466
L142
D
Y
L
N
D
Q
A
L
W
S
K
C
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507468
202
21691
S145
N
Y
L
M
D
H
S
S
W
G
N
C
L
Q
P
Chicken
Gallus gallus
XP_422848
203
21955
E146
G
Y
L
L
E
Y
N
E
W
S
K
C
Q
E
P
Frog
Xenopus laevis
NP_001087352
203
21675
S144
Q
Y
L
T
N
H
Q
S
W
S
T
C
S
E
P
Zebra Danio
Brachydanio rerio
NP_001003489
198
20755
M144
N
Y
L
S
N
R
T
M
W
E
L
C
A
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
98
47.2
N.A.
78.2
50
N.A.
83.6
64
71.9
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98
98.5
55.5
N.A.
90
68.8
N.A.
92
79.8
85.2
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
66.6
53.3
N.A.
46.6
53.3
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
66.6
N.A.
66.6
73.3
73.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% C
% Asp:
10
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
10
0
10
10
0
10
80
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% K
% Leu:
0
0
100
60
0
0
0
10
0
0
10
0
10
0
0
% L
% Met:
0
0
0
10
0
0
0
20
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
10
30
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% P
% Gln:
60
0
0
0
0
10
10
0
0
0
20
0
10
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
10
60
20
0
80
0
0
10
0
0
% S
% Thr:
0
0
0
10
0
40
10
40
0
0
10
0
30
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% W
% Tyr:
0
100
0
0
0
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _