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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKTR All Species: 5.45
Human Site: S1409 Identified Species: 17.14
UniProt: P30414 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30414 NP_005376.2 1462 165677 S1409 Y T Y D S Y Y S R S R S R S R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108826 2245 250920 Y1404 S Y T Y D S Y Y S R S R S R S
Dog Lupus familis XP_851976 2045 227439 P1953 H T G E K P Y P C D V C G Q R
Cat Felis silvestris
Mouse Mus musculus P30415 1453 163421 S1400 Y T Y D S Y Y S R S R S R S R
Rat Rattus norvegicus O55035 752 88360 K700 S S Q D N E V K S S T L K N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418494 1463 168702 L1408 Q S I Q V I H L X X L L X Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001338072 1394 158189 S1342 R G R Y R S R S D S Y D S Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733246 970 112777 D918 L H E E D S V D P D A A A S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 63 44.5 N.A. 78.8 27 N.A. N.A. 42.1 N.A. 42.7 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 63.7 54.6 N.A. 85.5 38.8 N.A. N.A. 55.4 N.A. 58 N.A. 41.3 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 20 N.A. 100 13.3 N.A. N.A. 0 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 6.6 33.3 N.A. 100 46.6 N.A. N.A. 20 N.A. 13.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 13 13 13 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 13 0 0 0 % C
% Asp: 0 0 0 38 25 0 0 13 13 25 0 13 0 0 0 % D
% Glu: 0 0 13 25 0 13 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 13 0 0 0 0 0 0 0 0 0 13 0 0 % G
% His: 13 13 0 0 0 0 13 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 13 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 13 0 0 13 0 0 0 0 13 0 13 % K
% Leu: 13 0 0 0 0 0 0 13 0 0 13 25 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 13 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 0 0 0 0 13 0 13 13 0 0 0 0 0 0 % P
% Gln: 13 0 13 13 0 0 0 0 0 0 0 0 0 25 13 % Q
% Arg: 13 0 13 0 13 0 13 0 25 13 25 13 25 13 38 % R
% Ser: 25 25 0 0 25 38 0 38 25 50 13 25 25 38 25 % S
% Thr: 0 38 13 0 0 0 0 0 0 0 13 0 0 0 0 % T
% Val: 0 0 0 0 13 0 25 0 0 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 25 13 25 25 0 25 50 13 0 0 13 0 0 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _