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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKTR
All Species:
13.64
Human Site:
S419
Identified Species:
42.86
UniProt:
P30414
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30414
NP_005376.2
1462
165677
S419
N
G
Y
Y
S
D
L
S
T
A
R
H
S
G
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108826
2245
250920
S411
N
G
Y
Y
S
D
L
S
T
A
R
H
S
D
G
Dog
Lupus familis
XP_851976
2045
227439
S484
N
G
Y
Y
S
D
L
S
T
A
R
H
S
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P30415
1453
163421
S419
N
G
Y
Y
S
D
L
S
T
A
R
H
S
D
G
Rat
Rattus norvegicus
O55035
752
88360
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418494
1463
168702
T418
N
G
Y
S
D
L
S
T
V
R
Y
S
S
H
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338072
1394
158189
R411
S
V
Y
S
S
Q
H
R
S
K
K
E
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733246
970
112777
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
63
44.5
N.A.
78.8
27
N.A.
N.A.
42.1
N.A.
42.7
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
63.7
54.6
N.A.
85.5
38.8
N.A.
N.A.
55.4
N.A.
58
N.A.
41.3
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
86.6
0
N.A.
N.A.
33.3
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
86.6
N.A.
86.6
0
N.A.
N.A.
40
N.A.
33.3
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
50
0
0
0
0
0
0
0
38
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
63
0
0
0
0
0
0
0
0
0
0
0
13
38
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
50
0
13
25
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
13
0
13
13
13
% K
% Leu:
0
0
0
0
0
13
50
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
13
50
0
0
0
0
% R
% Ser:
13
0
0
25
63
0
13
50
13
0
0
13
63
0
0
% S
% Thr:
0
0
0
0
0
0
0
13
50
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
75
50
0
0
0
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _