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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMT1
All Species:
35.76
Human Site:
S421
Identified Species:
56.19
UniProt:
P30419
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30419
NP_066565.1
496
56806
S421
K
S
L
K
A
A
Y
S
F
Y
N
V
H
T
Q
Chimpanzee
Pan troglodytes
XP_001143491
416
48122
M355
Q
T
P
L
L
D
L
M
S
D
A
L
V
L
A
Rhesus Macaque
Macaca mulatta
XP_001115181
500
57382
S425
K
S
L
K
A
A
Y
S
F
Y
N
V
H
T
Q
Dog
Lupus familis
XP_537613
496
56755
S421
K
S
L
K
A
A
Y
S
F
Y
N
V
H
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
O70310
496
56870
S421
K
S
L
K
A
A
Y
S
F
Y
N
V
H
T
Q
Rat
Rattus norvegicus
Q8K1Q0
496
56842
S421
K
S
L
K
A
A
Y
S
F
Y
N
V
H
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418088
495
56847
S420
K
S
L
K
A
A
Y
S
F
Y
N
V
H
T
K
Frog
Xenopus laevis
NP_001080192
484
55176
S409
K
S
L
K
A
A
Y
S
F
Y
S
V
H
T
K
Zebra Danio
Brachydanio rerio
NP_001018316
487
55671
S412
R
S
L
K
A
A
Y
S
F
Y
N
V
H
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61613
472
53814
S397
K
T
V
R
A
A
Y
S
F
Y
N
V
S
T
K
Honey Bee
Apis mellifera
XP_624861
471
54938
F397
T
L
R
A
A
Y
S
F
Y
N
V
S
T
A
T
Nematode Worm
Caenorhab. elegans
P46548
450
50870
I389
S
V
T
P
K
Q
L
I
N
D
S
L
I
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTR9
434
49780
N373
T
S
F
L
Q
L
M
N
D
A
L
I
V
S
K
Baker's Yeast
Sacchar. cerevisiae
P14743
455
52819
D394
L
A
K
N
A
N
M
D
V
F
N
A
L
T
S
Red Bread Mold
Neurospora crassa
Q7S3C8
569
64133
I464
R
H
P
K
H
N
S
I
R
A
A
Y
M
F
Y
Conservation
Percent
Protein Identity:
100
83.8
95.5
98.5
N.A.
97.3
97.3
N.A.
N.A.
90.1
82.4
82
N.A.
55
60
48.1
N.A.
Protein Similarity:
100
83.8
96.5
99.4
N.A.
98.3
98.5
N.A.
N.A.
93.3
89.5
88.7
N.A.
68.7
72.9
64.9
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
66.6
6.6
0
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
93.3
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.5
39.9
42.3
Protein Similarity:
N.A.
N.A.
N.A.
62.7
57.2
56.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
74
60
0
0
0
14
14
7
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
7
7
14
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
7
60
7
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
7
0
0
0
0
0
0
0
54
0
0
% H
% Ile:
0
0
0
0
0
0
0
14
0
0
0
7
7
0
0
% I
% Lys:
54
0
7
60
7
0
0
0
0
0
0
0
0
0
27
% K
% Leu:
7
7
54
14
7
7
14
0
0
0
7
14
7
14
0
% L
% Met:
0
0
0
0
0
0
14
7
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
7
0
14
0
7
7
7
60
0
0
0
0
% N
% Pro:
0
0
14
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
7
7
0
0
0
0
0
0
0
0
34
% Q
% Arg:
14
0
7
7
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
7
60
0
0
0
0
14
60
7
0
14
7
7
7
7
% S
% Thr:
14
14
7
0
0
0
0
0
0
0
0
0
7
67
14
% T
% Val:
0
7
7
0
0
0
0
0
7
0
7
60
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
60
0
7
60
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _