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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AVPR2
All Species:
9.7
Human Site:
S241
Identified Species:
23.7
UniProt:
P30518
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30518
NP_000045.1
371
40279
S241
A
S
L
V
P
G
P
S
E
R
P
G
G
R
R
Chimpanzee
Pan troglodytes
XP_525039
424
47111
S251
W
R
T
W
D
R
P
S
P
S
T
S
A
A
T
Rhesus Macaque
Macaca mulatta
P56494
389
42895
E245
A
A
A
A
E
A
P
E
G
A
A
A
G
D
G
Dog
Lupus familis
XP_545695
420
46143
L251
W
R
A
W
D
R
T
L
P
S
G
P
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
O88721
371
40627
S241
A
S
L
V
P
G
P
S
E
R
A
G
R
R
R
Rat
Rattus norvegicus
Q00788
371
40730
S241
A
S
L
V
P
G
P
S
E
R
A
G
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520272
381
41874
S255
R
R
R
W
P
L
G
S
R
E
G
R
G
G
R
Chicken
Gallus gallus
NP_001026650
370
42416
N242
N
I
Y
V
K
K
Q
N
E
Y
Q
V
T
N
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921565
389
44223
Q215
L
Y
L
K
T
Q
Q
Q
Q
R
G
D
E
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868T3
506
55785
V319
W
A
K
G
S
I
F
V
P
T
E
R
A
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
41.6
40.7
N.A.
87.5
87.8
N.A.
65.8
40.4
N.A.
43.1
N.A.
24.7
N.A.
N.A.
N.A.
Protein Similarity:
100
53.5
58.3
54.7
N.A.
89.7
89.7
N.A.
73.2
58.7
N.A.
58
N.A.
40.5
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
20
0
N.A.
86.6
86.6
N.A.
26.6
13.3
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
26.6
0
N.A.
86.6
86.6
N.A.
26.6
26.6
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
20
20
10
0
10
0
0
0
10
30
10
30
20
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
0
0
10
0
10
0
% D
% Glu:
0
0
0
0
10
0
0
10
40
10
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
10
0
30
10
0
10
0
30
30
30
30
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
40
0
0
10
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
40
0
50
0
30
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
20
10
10
0
10
0
0
0
10
% Q
% Arg:
10
30
10
0
0
20
0
0
10
40
0
20
20
30
40
% R
% Ser:
0
30
0
0
10
0
0
50
0
20
0
10
0
0
0
% S
% Thr:
0
0
10
0
10
0
10
0
0
10
10
0
10
0
10
% T
% Val:
0
0
0
40
0
0
0
10
0
0
0
10
0
0
0
% V
% Trp:
30
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _