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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMOX2
All Species:
12.12
Human Site:
T248
Identified Species:
26.67
UniProt:
P30519
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30519
NP_001120676.1
316
36033
T248
G
S
T
L
A
R
E
T
L
E
D
G
F
P
V
Chimpanzee
Pan troglodytes
XP_001168651
287
32819
G229
D
G
F
P
V
H
D
G
K
G
D
M
R
K
C
Rhesus Macaque
Macaca mulatta
XP_001096664
316
36032
T248
G
S
T
L
A
R
E
T
L
E
D
G
F
P
V
Dog
Lupus familis
XP_851743
316
35896
I248
G
S
L
L
A
R
E
I
L
E
D
G
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
O70252
315
35720
T247
G
S
M
L
A
R
E
T
L
E
D
G
L
P
V
Rat
Rattus norvegicus
P23711
315
35744
T247
G
S
M
L
T
K
E
T
L
E
D
G
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509849
363
40623
E248
S
V
G
P
K
G
E
E
I
T
S
G
W
C
Q
Chicken
Gallus gallus
P14791
296
33491
A238
G
H
A
V
Q
P
K
A
E
L
R
T
R
S
V
Frog
Xenopus laevis
NP_001085675
266
30452
K208
L
D
L
D
M
E
T
K
E
S
I
V
Q
E
A
Zebra Danio
Brachydanio rerio
NP_001096609
310
34397
V243
G
K
D
I
E
E
E
V
Q
D
I
G
P
H
A
Tiger Blowfish
Takifugu rubipres
O73688
277
31192
D219
F
N
I
Q
V
F
E
D
L
Q
K
M
L
N
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99
90.1
N.A.
87.9
88.6
N.A.
64.1
50.3
58.2
54.1
41.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.8
99.6
95.8
N.A.
93.3
93.6
N.A.
74.9
67
70.2
71.1
59.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
86.6
73.3
N.A.
13.3
13.3
0
20
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
80
N.A.
86.6
80
N.A.
26.6
26.6
0
33.3
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
37
0
0
10
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
10
10
10
10
0
0
10
10
0
10
55
0
0
0
0
% D
% Glu:
0
0
0
0
10
19
73
10
19
46
0
0
0
10
0
% E
% Phe:
10
0
10
0
0
10
0
0
0
0
0
0
19
0
0
% F
% Gly:
64
10
10
0
0
10
0
10
0
10
0
64
0
0
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
10
0
0
0
10
10
0
19
0
0
0
0
% I
% Lys:
0
10
0
0
10
10
10
10
10
0
10
0
0
10
0
% K
% Leu:
10
0
19
46
0
0
0
0
55
10
0
0
28
0
0
% L
% Met:
0
0
19
0
10
0
0
0
0
0
0
19
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
19
0
10
0
0
0
0
0
0
10
46
0
% P
% Gln:
0
0
0
10
10
0
0
0
10
10
0
0
10
0
10
% Q
% Arg:
0
0
0
0
0
37
0
0
0
0
10
0
19
0
0
% R
% Ser:
10
46
0
0
0
0
0
0
0
10
10
0
0
10
0
% S
% Thr:
0
0
19
0
10
0
10
37
0
10
0
10
0
0
0
% T
% Val:
0
10
0
10
19
0
0
10
0
0
0
10
10
0
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _