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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSS
All Species:
42.12
Human Site:
S448
Identified Species:
57.92
UniProt:
P30520
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30520
NP_001117.2
456
50097
S448
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Chimpanzee
Pan troglodytes
XP_514311
599
65172
Y585
H
F
M
A
F
S
L
Y
R
F
V
G
I
D
G
Rhesus Macaque
Macaca mulatta
XP_001102992
579
62702
S571
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Dog
Lupus familis
XP_537220
456
50005
S448
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P46664
456
50003
S448
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Rat
Rattus norvegicus
NP_001099445
456
50067
S448
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513692
453
49781
S445
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Chicken
Gallus gallus
NP_001026692
451
49436
S443
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Frog
Xenopus laevis
NP_001080088
457
50062
S449
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Zebra Danio
Brachydanio rerio
NP_001017804
455
49701
S447
K
W
I
G
V
G
K
S
R
E
S
M
I
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y2
447
48882
G439
R
W
V
G
V
G
K
G
R
E
S
I
I
N
V
Honey Bee
Apis mellifera
XP_392818
449
49264
G442
K
W
I
G
V
G
A
G
R
E
S
V
I
T
L
Nematode Worm
Caenorhab. elegans
P91134
434
47690
E425
V
Y
I
G
V
G
A
E
R
E
S
L
I
V
R
Sea Urchin
Strong. purpuratus
XP_787094
432
47877
S424
K
W
V
G
I
G
K
S
R
D
S
I
I
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24578
484
51895
G477
H
Y
I
G
V
G
P
G
R
D
A
L
I
Y
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96529
490
52946
G483
H
Y
I
G
I
G
P
G
R
D
A
L
I
Y
K
Baker's Yeast
Sacchar. cerevisiae
P80210
433
48261
A423
E
W
V
G
T
G
P
A
R
E
S
M
L
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
77.8
98
N.A.
96.7
97.3
N.A.
85.5
89.4
82.9
82.4
N.A.
60
60.9
51.3
63.1
Protein Similarity:
100
73.7
78.2
98.4
N.A.
98.4
98.9
N.A.
89.6
94
92.1
90.3
N.A.
74.1
75.4
67.1
78.9
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
60
73.3
53.3
73.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
80
66.6
100
Percent
Protein Identity:
N.A.
46.2
N.A.
44.9
53.9
N.A.
Protein Similarity:
N.A.
65.2
N.A.
63.2
69.9
N.A.
P-Site Identity:
N.A.
40
N.A.
33.3
46.6
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
0
12
6
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
18
0
0
0
6
0
% D
% Glu:
6
0
0
0
0
0
0
6
0
77
0
0
0
0
0
% E
% Phe:
0
6
0
0
6
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
0
0
0
95
0
95
0
24
0
0
0
6
0
0
6
% G
% His:
18
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% H
% Ile:
0
0
77
0
12
0
0
0
0
0
0
12
95
0
0
% I
% Lys:
65
0
0
0
0
0
65
0
0
0
0
0
0
0
18
% K
% Leu:
0
0
0
0
0
0
6
0
0
0
0
18
6
0
65
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
59
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
18
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
0
% Q
% Arg:
6
0
0
0
0
0
0
0
100
0
0
0
0
0
6
% R
% Ser:
0
0
0
0
0
6
0
59
0
0
83
0
0
0
0
% S
% Thr:
0
0
0
0
6
0
0
0
0
0
0
0
0
6
0
% T
% Val:
6
0
18
0
77
0
0
0
0
0
6
6
0
6
6
% V
% Trp:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
18
0
0
0
0
0
6
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _