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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSS
All Species:
49.73
Human Site:
S451
Identified Species:
68.38
UniProt:
P30520
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30520
NP_001117.2
456
50097
S451
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Chimpanzee
Pan troglodytes
XP_514311
599
65172
V588
A
F
S
L
Y
R
F
V
G
I
D
G
Y
L
K
Rhesus Macaque
Macaca mulatta
XP_001102992
579
62702
S574
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Dog
Lupus familis
XP_537220
456
50005
S451
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P46664
456
50003
S451
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Rat
Rattus norvegicus
NP_001099445
456
50067
S451
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513692
453
49781
S448
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Chicken
Gallus gallus
NP_001026692
451
49436
S446
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Frog
Xenopus laevis
NP_001080088
457
50062
S452
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Zebra Danio
Brachydanio rerio
NP_001017804
455
49701
S450
G
V
G
K
S
R
E
S
M
I
Q
L
F
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y2
447
48882
S442
G
V
G
K
G
R
E
S
I
I
N
V
H
_
_
Honey Bee
Apis mellifera
XP_392818
449
49264
Nematode Worm
Caenorhab. elegans
P91134
434
47690
S428
G
V
G
A
E
R
E
S
L
I
V
R
Q
Q
_
Sea Urchin
Strong. purpuratus
XP_787094
432
47877
S427
G
I
G
K
S
R
D
S
I
I
Q
L
F
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24578
484
51895
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96529
490
52946
Baker's Yeast
Sacchar. cerevisiae
P80210
433
48261
S426
G
T
G
P
A
R
E
S
M
L
H
K
E
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
77.8
98
N.A.
96.7
97.3
N.A.
85.5
89.4
82.9
82.4
N.A.
60
60.9
51.3
63.1
Protein Similarity:
100
73.7
78.2
98.4
N.A.
98.4
98.9
N.A.
89.6
94
92.1
90.3
N.A.
74.1
75.4
67.1
78.9
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
61.5
0
50
76.9
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
76.9
0
57.1
100
Percent
Protein Identity:
N.A.
46.2
N.A.
44.9
53.9
N.A.
Protein Similarity:
N.A.
65.2
N.A.
63.2
69.9
N.A.
P-Site Identity:
N.A.
0
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
6
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
0
0
6
0
0
0
0
% D
% Glu:
0
0
0
0
6
0
71
0
0
0
0
0
6
0
0
% E
% Phe:
0
6
0
0
0
0
6
0
0
0
0
0
59
0
0
% F
% Gly:
77
0
77
0
6
0
0
0
6
0
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% H
% Ile:
0
6
0
0
0
0
0
0
12
77
0
0
0
6
0
% I
% Lys:
0
0
0
65
0
0
0
0
0
0
0
6
0
0
12
% K
% Leu:
0
0
0
6
0
0
0
0
6
6
0
59
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% N
% Pro:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
59
0
6
6
0
% Q
% Arg:
0
0
0
0
0
83
0
0
0
0
0
6
0
0
0
% R
% Ser:
0
0
6
0
59
0
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
65
0
0
0
0
0
6
0
0
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
65
71
% _