Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADSS All Species: 48.48
Human Site: T208 Identified Species: 66.67
UniProt: P30520 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30520 NP_001117.2 456 50097 T208 Q Y K S I Y P T L E I D I E G
Chimpanzee Pan troglodytes XP_514311 599 65172 T342 Q Y K S I Y P T L E I D I E G
Rhesus Macaque Macaca mulatta XP_001102992 579 62702 T331 Q Y K S I Y P T L E I D I E G
Dog Lupus familis XP_537220 456 50005 T208 Q Y K S I Y P T L E I D I E G
Cat Felis silvestris
Mouse Mus musculus P46664 456 50003 T208 Q Y K S I Y P T L E I D I E G
Rat Rattus norvegicus NP_001099445 456 50067 T208 Q Y K S I Y P T L E I D I E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513692 453 49781 T205 Q Y K S M Y P T L E I D I E G
Chicken Gallus gallus NP_001026692 451 49436 T203 Q Y K A I Y P T L E I D I E G
Frog Xenopus laevis NP_001080088 457 50062 S209 Q Y K S M Y P S L E I D I D G
Zebra Danio Brachydanio rerio NP_001017804 455 49701 S207 Q Y K S M Y P S L E I D V D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0Y2 447 48882 S199 T H V R L F P S I N V D V E A
Honey Bee Apis mellifera XP_392818 449 49264 A203 S Y Q K M F P A L Q V D I K A
Nematode Worm Caenorhab. elegans P91134 434 47690 S184 H Y K K Q F P S I E V N V D E
Sea Urchin Strong. purpuratus XP_787094 432 47877 Q184 I H Q K L F P Q L V V D V E S
Poplar Tree Populus trichocarpa
Maize Zea mays O24578 484 51895 Y237 S R F Q G F Q Y S K S L L K E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96529 490 52946 F241 A A A R F Q G F K Y T P E M L
Baker's Yeast Sacchar. cerevisiae P80210 433 48261 Q180 R L L E T R R Q R Y G D F E Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.7 77.8 98 N.A. 96.7 97.3 N.A. 85.5 89.4 82.9 82.4 N.A. 60 60.9 51.3 63.1
Protein Similarity: 100 73.7 78.2 98.4 N.A. 98.4 98.9 N.A. 89.6 94 92.1 90.3 N.A. 74.1 75.4 67.1 78.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 80 73.3 N.A. 20 33.3 26.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 73.3 73.3 66.6
Percent
Protein Identity: N.A. 46.2 N.A. 44.9 53.9 N.A.
Protein Similarity: N.A. 65.2 N.A. 63.2 69.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 13.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 6 6 0 0 0 6 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 83 0 18 0 % D
% Glu: 0 0 0 6 0 0 0 0 0 65 0 0 6 65 12 % E
% Phe: 0 0 6 0 6 30 0 6 0 0 0 0 6 0 0 % F
% Gly: 0 0 0 0 6 0 6 0 0 0 6 0 0 0 59 % G
% His: 6 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 0 0 42 0 0 0 12 0 59 0 59 0 0 % I
% Lys: 0 0 65 18 0 0 0 0 6 6 0 0 0 12 0 % K
% Leu: 0 6 6 0 12 0 0 0 71 0 0 6 6 0 6 % L
% Met: 0 0 0 0 24 0 0 0 0 0 0 0 0 6 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 6 0 6 0 0 0 % N
% Pro: 0 0 0 0 0 0 83 0 0 0 0 6 0 0 0 % P
% Gln: 59 0 12 6 6 6 6 12 0 6 0 0 0 0 0 % Q
% Arg: 6 6 0 12 0 6 6 0 6 0 0 0 0 0 0 % R
% Ser: 12 0 0 53 0 0 0 24 6 0 6 0 0 0 6 % S
% Thr: 6 0 0 0 6 0 0 48 0 0 6 0 0 0 0 % T
% Val: 0 0 6 0 0 0 0 0 0 6 24 0 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 71 0 0 0 59 0 6 0 12 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _