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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSS
All Species:
47.88
Human Site:
T404
Identified Species:
65.83
UniProt:
P30520
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30520
NP_001117.2
456
50097
T404
K
V
E
V
Q
Y
K
T
L
P
G
W
N
T
D
Chimpanzee
Pan troglodytes
XP_514311
599
65172
T538
K
V
E
V
Q
Y
K
T
L
P
G
W
N
T
D
Rhesus Macaque
Macaca mulatta
XP_001102992
579
62702
T527
K
V
E
V
Q
Y
K
T
L
P
G
W
N
T
D
Dog
Lupus familis
XP_537220
456
50005
T404
K
V
E
V
Q
Y
K
T
L
P
G
W
N
T
D
Cat
Felis silvestris
Mouse
Mus musculus
P46664
456
50003
T404
K
V
E
V
Q
Y
K
T
L
P
G
W
N
T
D
Rat
Rattus norvegicus
NP_001099445
456
50067
T404
K
V
E
V
Q
Y
K
T
L
P
G
W
N
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513692
453
49781
T401
K
V
E
V
Q
Y
Q
T
L
P
G
W
N
T
D
Chicken
Gallus gallus
NP_001026692
451
49436
T399
K
V
E
V
K
Y
E
T
L
P
G
W
D
T
D
Frog
Xenopus laevis
NP_001080088
457
50062
T405
K
V
E
V
E
Y
E
T
L
P
G
W
N
K
D
Zebra Danio
Brachydanio rerio
NP_001017804
455
49701
T403
K
V
E
V
E
Y
E
T
L
P
G
W
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y2
447
48882
V395
N
I
E
V
E
Y
A
V
L
P
G
W
Q
T
S
Honey Bee
Apis mellifera
XP_392818
449
49264
T398
K
V
E
V
I
Y
E
T
L
D
G
W
Q
S
T
Nematode Worm
Caenorhab. elegans
P91134
434
47690
E381
A
I
E
V
E
Y
K
E
F
E
G
W
N
E
P
Sea Urchin
Strong. purpuratus
XP_787094
432
47877
T380
E
V
E
V
E
Y
V
T
M
P
G
W
N
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24578
484
51895
V433
Q
V
Q
V
N
Y
E
V
L
P
G
W
Q
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96529
490
52946
V439
E
L
H
V
E
Y
E
V
L
P
G
W
K
S
D
Baker's Yeast
Sacchar. cerevisiae
P80210
433
48261
V379
K
V
E
V
E
Y
K
V
L
P
G
W
D
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
77.8
98
N.A.
96.7
97.3
N.A.
85.5
89.4
82.9
82.4
N.A.
60
60.9
51.3
63.1
Protein Similarity:
100
73.7
78.2
98.4
N.A.
98.4
98.9
N.A.
89.6
94
92.1
90.3
N.A.
74.1
75.4
67.1
78.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
80
80
80
N.A.
53.3
60
46.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
66.6
73.3
60
86.6
Percent
Protein Identity:
N.A.
46.2
N.A.
44.9
53.9
N.A.
Protein Similarity:
N.A.
65.2
N.A.
63.2
69.9
N.A.
P-Site Identity:
N.A.
53.3
N.A.
46.6
73.3
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
6
0
0
12
0
77
% D
% Glu:
12
0
89
0
42
0
36
6
0
6
0
0
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
6
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
71
0
0
0
6
0
48
0
0
0
0
0
6
6
0
% K
% Leu:
0
6
0
0
0
0
0
0
89
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
6
0
0
0
0
0
0
0
59
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
6
% P
% Gln:
6
0
6
0
42
0
6
0
0
0
0
0
18
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
6
18
12
% S
% Thr:
0
0
0
0
0
0
0
71
0
0
0
0
0
65
6
% T
% Val:
0
83
0
100
0
0
6
24
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% W
% Tyr:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _