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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSS
All Species:
40.61
Human Site:
Y239
Identified Species:
55.83
UniProt:
P30520
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30520
NP_001117.2
456
50097
Y239
R
D
G
V
Y
F
L
Y
E
A
L
H
G
P
P
Chimpanzee
Pan troglodytes
XP_514311
599
65172
Y373
R
D
G
V
Y
F
L
Y
E
A
L
H
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001102992
579
62702
Y362
R
D
G
V
Y
F
L
Y
E
A
L
H
G
P
P
Dog
Lupus familis
XP_537220
456
50005
Y239
R
D
G
V
Y
F
L
Y
E
A
L
H
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P46664
456
50003
Y239
K
D
G
V
Y
F
L
Y
E
A
L
H
G
P
P
Rat
Rattus norvegicus
NP_001099445
456
50067
Y239
R
D
G
V
Y
F
L
Y
E
A
L
H
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513692
453
49781
Y236
R
D
G
V
Y
F
I
Y
E
A
L
H
G
P
P
Chicken
Gallus gallus
NP_001026692
451
49436
Y234
K
D
G
V
Y
F
M
Y
E
A
L
H
G
P
P
Frog
Xenopus laevis
NP_001080088
457
50062
Y240
K
D
G
V
Y
Y
I
Y
E
A
L
H
G
P
P
Zebra Danio
Brachydanio rerio
NP_001017804
455
49701
Y238
R
D
G
V
F
F
M
Y
E
A
L
H
G
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y2
447
48882
H230
K
D
T
I
C
F
L
H
T
A
L
R
N
G
K
Honey Bee
Apis mellifera
XP_392818
449
49264
H234
K
E
T
V
Q
Y
L
H
Q
A
L
R
E
G
K
Nematode Worm
Caenorhab. elegans
P91134
434
47690
F215
L
V
G
D
T
V
G
F
I
H
E
Q
R
N
A
Sea Urchin
Strong. purpuratus
XP_787094
432
47877
D215
C
D
T
V
Y
L
L
D
S
L
L
K
E
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24578
484
51895
N268
A
D
T
V
H
V
L
N
E
S
I
K
Q
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96529
490
52946
F272
Y
I
T
D
T
V
H
F
I
N
D
S
I
S
Q
Baker's Yeast
Sacchar. cerevisiae
P80210
433
48261
V211
K
P
F
V
V
D
S
V
V
F
M
H
N
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
77.8
98
N.A.
96.7
97.3
N.A.
85.5
89.4
82.9
82.4
N.A.
60
60.9
51.3
63.1
Protein Similarity:
100
73.7
78.2
98.4
N.A.
98.4
98.9
N.A.
89.6
94
92.1
90.3
N.A.
74.1
75.4
67.1
78.9
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
86.6
80
80
N.A.
33.3
26.6
6.6
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
53.3
60
13.3
40
Percent
Protein Identity:
N.A.
46.2
N.A.
44.9
53.9
N.A.
Protein Similarity:
N.A.
65.2
N.A.
63.2
69.9
N.A.
P-Site Identity:
N.A.
26.6
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
0
0
0
71
0
0
0
6
6
% A
% Cys:
6
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
77
0
12
0
6
0
6
0
0
6
0
0
6
0
% D
% Glu:
0
6
0
0
0
0
0
0
65
0
6
0
12
0
0
% E
% Phe:
0
0
6
0
6
59
0
12
0
6
0
0
0
0
0
% F
% Gly:
0
0
65
0
0
0
6
0
0
0
0
0
59
12
0
% G
% His:
0
0
0
0
6
0
6
12
0
6
0
65
0
0
0
% H
% Ile:
0
6
0
6
0
0
12
0
12
0
6
0
6
0
6
% I
% Lys:
36
0
0
0
0
0
0
0
0
0
0
12
0
6
24
% K
% Leu:
6
0
0
0
0
6
59
0
0
6
77
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
6
0
0
12
6
0
% N
% Pro:
0
6
0
0
0
0
0
0
0
0
0
0
0
59
59
% P
% Gln:
0
0
0
0
6
0
0
0
6
0
0
6
6
0
6
% Q
% Arg:
42
0
0
0
0
0
0
0
0
0
0
12
6
0
0
% R
% Ser:
0
0
0
0
0
0
6
0
6
6
0
6
0
6
0
% S
% Thr:
0
0
30
0
12
0
0
0
6
0
0
0
0
0
0
% T
% Val:
0
6
0
83
6
18
0
6
6
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
59
12
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _