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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADSS All Species: 49.39
Human Site: Y294 Identified Species: 67.92
UniProt: P30520 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30520 NP_001117.2 456 50097 Y294 P Q N V G E V Y G V V K A Y T
Chimpanzee Pan troglodytes XP_514311 599 65172 Y428 P Q N V G E V Y G V V K A Y T
Rhesus Macaque Macaca mulatta XP_001102992 579 62702 Y417 P Q N V G E V Y G V V K A Y T
Dog Lupus familis XP_537220 456 50005 Y294 P Q N V G E V Y G V V K A Y T
Cat Felis silvestris
Mouse Mus musculus P46664 456 50003 Y294 P Q N V G E V Y G V V K A Y T
Rat Rattus norvegicus NP_001099445 456 50067 Y294 P Q N V G E V Y G V V K A Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513692 453 49781 Y291 P Q N V G E V Y G V V K A Y T
Chicken Gallus gallus NP_001026692 451 49436 Y289 P Q N V G E V Y G V V K A Y T
Frog Xenopus laevis NP_001080088 457 50062 Y295 P Q S I G D V Y G V V K A Y T
Zebra Danio Brachydanio rerio NP_001017804 455 49701 Y293 P Q N V G E V Y G V V K A Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0Y2 447 48882 I284 P Q T I G E V I G V V K A Y T
Honey Bee Apis mellifera XP_392818 449 49264 V288 P S Y I G E V V G V V K A Y T
Nematode Worm Caenorhab. elegans P91134 434 47690 I271 P T A V G N V I G V V K A Y Q
Sea Urchin Strong. purpuratus XP_787094 432 47877 Y270 P R S I G E V Y G V V K A Y T
Poplar Tree Populus trichocarpa
Maize Zea mays O24578 484 51895 I322 P R A I G D L I G V V K A Y T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96529 490 52946 I328 P S V V G D L I G V V K A Y T
Baker's Yeast Sacchar. cerevisiae P80210 433 48261 Y269 P R T I D E I Y G V V K A Y T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.7 77.8 98 N.A. 96.7 97.3 N.A. 85.5 89.4 82.9 82.4 N.A. 60 60.9 51.3 63.1
Protein Similarity: 100 73.7 78.2 98.4 N.A. 98.4 98.9 N.A. 89.6 94 92.1 90.3 N.A. 74.1 75.4 67.1 78.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 80 100 N.A. 80 73.3 66.6 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 80 66.6 100
Percent
Protein Identity: N.A. 46.2 N.A. 44.9 53.9 N.A.
Protein Similarity: N.A. 65.2 N.A. 63.2 69.9 N.A.
P-Site Identity: N.A. 60 N.A. 66.6 66.6 N.A.
P-Site Similarity: N.A. 86.6 N.A. 80 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 0 0 0 100 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 6 18 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 95 0 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 36 0 0 6 24 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % K
% Leu: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 53 0 0 6 0 0 0 0 0 0 0 0 0 % N
% Pro: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 65 0 0 0 0 0 0 0 0 0 0 0 0 6 % Q
% Arg: 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 6 12 0 0 0 0 0 0 0 0 0 0 0 95 % T
% Val: 0 0 6 65 0 0 83 6 0 100 100 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 71 0 0 0 0 0 100 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _