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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSS
All Species:
60.61
Human Site:
Y428
Identified Species:
83.33
UniProt:
P30520
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30520
NP_001117.2
456
50097
Y428
L
P
V
N
A
Q
N
Y
V
R
F
I
E
D
E
Chimpanzee
Pan troglodytes
XP_514311
599
65172
Y562
L
P
V
N
A
Q
N
Y
V
R
F
I
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001102992
579
62702
Y551
L
P
V
N
A
Q
N
Y
V
R
F
I
E
D
E
Dog
Lupus familis
XP_537220
456
50005
Y428
L
P
I
N
A
Q
N
Y
V
R
F
I
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P46664
456
50003
Y428
L
P
V
N
A
Q
N
Y
V
R
F
I
E
D
E
Rat
Rattus norvegicus
NP_001099445
456
50067
Y428
L
P
V
N
A
Q
N
Y
V
R
F
I
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513692
453
49781
Y425
L
P
V
N
A
Q
N
Y
V
L
F
I
E
K
E
Chicken
Gallus gallus
NP_001026692
451
49436
Y423
L
P
V
N
A
Q
N
Y
V
R
F
I
E
M
E
Frog
Xenopus laevis
NP_001080088
457
50062
Y429
L
P
E
N
A
K
K
Y
V
Q
F
I
K
E
E
Zebra Danio
Brachydanio rerio
NP_001017804
455
49701
Y427
L
P
E
N
A
K
K
Y
V
C
F
I
E
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y2
447
48882
Y419
L
P
E
N
A
Q
S
Y
V
R
L
L
E
S
E
Honey Bee
Apis mellifera
XP_392818
449
49264
Y422
L
P
P
N
A
K
K
Y
I
Q
L
I
E
E
H
Nematode Worm
Caenorhab. elegans
P91134
434
47690
Y405
L
P
E
K
C
R
Q
Y
V
K
F
I
E
D
F
Sea Urchin
Strong. purpuratus
XP_787094
432
47877
Y404
L
P
V
N
A
Q
K
Y
V
R
K
A
E
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24578
484
51895
Y457
L
P
Q
A
A
R
L
Y
V
E
R
I
E
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96529
490
52946
Y463
L
P
K
A
A
Q
Q
Y
V
E
R
I
E
E
L
Baker's Yeast
Sacchar. cerevisiae
P80210
433
48261
Y403
L
P
E
N
A
K
K
Y
L
K
Y
I
E
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.7
77.8
98
N.A.
96.7
97.3
N.A.
85.5
89.4
82.9
82.4
N.A.
60
60.9
51.3
63.1
Protein Similarity:
100
73.7
78.2
98.4
N.A.
98.4
98.9
N.A.
89.6
94
92.1
90.3
N.A.
74.1
75.4
67.1
78.9
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
93.3
60
66.6
N.A.
66.6
46.6
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
86.6
73.3
N.A.
80
73.3
66.6
73.3
Percent
Protein Identity:
N.A.
46.2
N.A.
44.9
53.9
N.A.
Protein Similarity:
N.A.
65.2
N.A.
63.2
69.9
N.A.
P-Site Identity:
N.A.
46.6
N.A.
53.3
53.3
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
95
0
0
0
0
0
0
6
0
0
0
% A
% Cys:
0
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
53
0
% D
% Glu:
0
0
30
0
0
0
0
0
0
12
0
0
95
30
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
0
0
6
0
0
0
0
0
6
0
0
89
0
0
0
% I
% Lys:
0
0
6
6
0
24
30
0
0
12
6
0
6
6
0
% K
% Leu:
100
0
0
0
0
0
6
0
6
6
12
6
0
0
18
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
0
83
0
0
48
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
6
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
6
0
0
65
12
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
53
12
0
0
0
6
% R
% Ser:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
48
0
0
0
0
0
89
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _