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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A1
All Species:
15.45
Human Site:
S18
Identified Species:
30.91
UniProt:
P30531
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30531
NP_003033.3
599
67074
S18
G
Q
I
S
T
E
V
S
E
A
P
V
A
N
D
Chimpanzee
Pan troglodytes
XP_516280
599
67165
S18
G
Q
I
S
T
E
V
S
E
A
P
V
A
N
D
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
S48
G
Q
I
S
N
G
Y
S
A
V
P
S
P
G
A
Dog
Lupus familis
XP_541770
599
67007
S18
G
Q
I
S
T
E
V
S
E
A
P
V
A
N
D
Cat
Felis silvestris
Mouse
Mus musculus
P31649
602
68267
C18
N
G
E
T
K
P
V
C
P
A
M
E
K
V
E
Rat
Rattus norvegicus
P23978
599
66983
S18
G
Q
I
S
T
E
V
S
E
A
P
V
A
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414303
598
67057
D18
G
Q
I
S
T
E
V
D
A
S
I
T
N
D
K
Frog
Xenopus laevis
A7Y2X0
790
87434
A108
P
A
K
N
S
S
M
A
E
S
N
G
Q
T
N
Zebra Danio
Brachydanio rerio
NP_001007363
600
67102
N18
G
H
V
L
T
E
V
N
E
A
P
T
A
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51905
622
69307
E34
D
K
E
S
P
N
N
E
D
D
S
N
E
D
D
Honey Bee
Apis mellifera
NP_001128406
611
69338
A20
P
E
N
P
D
K
T
A
L
N
L
T
S
A
S
Nematode Worm
Caenorhab. elegans
NP_505873
610
69295
I20
W
S
S
W
A
D
F
I
M
S
C
I
G
Y
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
41.5
99
N.A.
51.8
98
N.A.
N.A.
93.1
38.2
85
N.A.
43.7
56.9
50.3
N.A.
Protein Similarity:
100
99.1
61.7
99.5
N.A.
69.9
99.5
N.A.
N.A.
96.6
53.6
92.3
N.A.
62.7
74.3
70.9
N.A.
P-Site Identity:
100
100
40
100
N.A.
13.3
93.3
N.A.
N.A.
46.6
6.6
66.6
N.A.
13.3
0
0
N.A.
P-Site Similarity:
100
100
40
100
N.A.
26.6
100
N.A.
N.A.
60
46.6
80
N.A.
33.3
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
17
17
50
0
0
42
9
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
0
9
9
0
9
9
9
0
0
0
17
50
% D
% Glu:
0
9
17
0
0
50
0
9
50
0
0
9
9
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
59
9
0
0
0
9
0
0
0
0
0
9
9
9
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
0
0
0
0
9
0
0
9
9
0
0
0
% I
% Lys:
0
9
9
0
9
9
0
0
0
0
0
0
9
0
9
% K
% Leu:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% M
% Asn:
9
0
9
9
9
9
9
9
0
9
9
9
9
34
9
% N
% Pro:
17
0
0
9
9
9
0
0
9
0
50
0
9
0
0
% P
% Gln:
0
50
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
59
9
9
0
42
0
25
9
9
9
9
9
% S
% Thr:
0
0
0
9
50
0
9
0
0
0
0
25
0
9
0
% T
% Val:
0
0
9
0
0
0
59
0
0
9
0
34
0
9
0
% V
% Trp:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _