KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA5
All Species:
22.42
Human Site:
T375
Identified Species:
44.85
UniProt:
P30532
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30532
NP_000736.2
468
53054
T375
S
H
V
D
R
Y
F
T
Q
K
E
E
T
E
S
Chimpanzee
Pan troglodytes
Q5IS51
468
53049
T375
S
H
V
D
R
Y
F
T
Q
K
E
E
T
E
S
Rhesus Macaque
Macaca mulatta
XP_001108279
466
52613
T373
S
H
V
D
R
Y
F
T
Q
K
E
E
T
E
S
Dog
Lupus familis
XP_539233
624
69375
A532
S
H
A
D
R
Y
F
A
Q
A
G
T
G
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q2MKA5
467
53430
T375
S
H
A
D
R
Y
F
T
Q
R
E
E
A
E
K
Rat
Rattus norvegicus
P20420
452
51856
T360
S
H
A
D
R
Y
F
T
Q
R
E
E
A
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513156
484
55206
T391
S
H
V
D
R
Y
F
T
Q
K
E
E
T
E
D
Chicken
Gallus gallus
P26152
454
51939
A361
S
H
V
D
R
Y
F
A
Q
K
E
E
K
G
N
Frog
Xenopus laevis
P05377
457
52088
K356
M
K
R
P
S
Q
E
K
Q
P
Q
K
T
F
A
Zebra Danio
Brachydanio rerio
Q98880
456
52082
R356
M
K
R
P
S
Q
E
R
Q
E
K
R
L
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
Y370
T
Q
Y
T
L
P
D
Y
D
D
S
T
P
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
S384
P
Q
P
P
G
H
H
S
K
P
N
R
K
F
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.3
67.4
N.A.
89
86.1
N.A.
83.4
82
42.5
42.7
N.A.
42
N.A.
41.8
N.A.
Protein Similarity:
100
99.1
96.5
70.8
N.A.
93.5
90.1
N.A.
87.1
88.6
60.9
59.4
N.A.
60.8
N.A.
58.9
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
73.3
80
N.A.
93.3
73.3
13.3
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
80
86.6
N.A.
93.3
80
33.3
20
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
17
0
9
0
0
17
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
67
0
0
9
0
9
9
0
0
0
0
17
% D
% Glu:
0
0
0
0
0
0
17
0
0
9
59
59
0
50
0
% E
% Phe:
0
0
0
0
0
0
67
0
0
0
0
0
0
25
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
9
0
9
17
0
% G
% His:
0
67
0
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
0
0
9
9
42
9
9
17
0
9
% K
% Leu:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% N
% Pro:
9
0
9
25
0
9
0
0
0
17
0
0
9
0
9
% P
% Gln:
0
17
0
0
0
17
0
0
84
0
9
0
0
0
0
% Q
% Arg:
0
0
17
0
67
0
0
9
0
17
0
17
0
0
0
% R
% Ser:
67
0
0
0
17
0
0
9
0
0
9
0
0
9
34
% S
% Thr:
9
0
0
9
0
0
0
50
0
0
0
17
42
0
0
% T
% Val:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
67
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _