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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSPO All Species: 32.42
Human Site: Y34 Identified Species: 71.33
UniProt: P30536 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30536 NP_000705.2 169 18779 Y34 H G E G L R W Y A G L Q K P S
Chimpanzee Pan troglodytes XP_001171791 169 18796 Y34 H G E G L R W Y A G L Q K P S
Rhesus Macaque Macaca mulatta XP_001108482 169 18799 Y34 H G E G L R W Y A G L Q K P S
Dog Lupus familis XP_531704 169 18732 Y34 R G E G L R W Y A S L Q K P S
Cat Felis silvestris
Mouse Mus musculus P50637 169 18822 Y34 R G E G L R W Y A S L Q K P S
Rat Rattus norvegicus P16257 169 18922 Y34 R G E G L R W Y A S L Q K P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416451 166 18558 Y36 R R E I P V W Y E S L R K P S
Frog Xenopus laevis NP_001080225 164 18362 Y33 R K E V K T W Y T T L V K P S
Zebra Danio Brachydanio rerio NP_001006032 162 18258 Y31 R R E V K T W Y S T L N K P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397432 171 19466 Y35 R K N I K P W Y E S L K K P T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788612 163 18063 Y33 G P E K M A W Y D T L K K P W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.2 81.6 N.A. 81 79.8 N.A. N.A. 59.7 57.4 53.2 N.A. N.A. 40.9 N.A. 40.8
Protein Similarity: 100 98.8 98.8 88.1 N.A. 86.3 87.5 N.A. N.A. 71.5 69.8 66.2 N.A. N.A. 59.6 N.A. 55.6
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. 46.6 46.6 46.6 N.A. N.A. 33.3 N.A. 40
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. 53.3 46.6 53.3 N.A. N.A. 46.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 55 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 91 0 0 0 0 0 19 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 55 0 55 0 0 0 0 0 28 0 0 0 0 0 % G
% His: 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 0 10 28 0 0 0 0 0 0 19 100 0 0 % K
% Leu: 0 0 0 0 55 0 0 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 0 0 10 10 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % Q
% Arg: 64 19 0 0 0 55 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 46 0 0 0 0 82 % S
% Thr: 0 0 0 0 0 19 0 0 10 28 0 0 0 0 10 % T
% Val: 0 0 0 19 0 10 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _