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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSL
All Species:
43.94
Human Site:
T354
Identified Species:
87.88
UniProt:
P30566
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30566
NP_000017.1
484
54889
T354
T
A
D
T
I
L
N
T
L
Q
N
I
S
E
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531727
490
55391
T360
T
A
D
A
I
L
N
T
L
Q
N
I
S
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P54822
484
54790
T354
T
A
D
T
I
L
N
T
L
Q
N
I
S
E
G
Rat
Rattus norvegicus
NP_001123975
484
54834
T354
T
A
D
T
I
L
T
T
L
Q
N
V
S
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21265
485
54634
T355
T
A
D
I
I
L
S
T
L
Q
N
I
S
E
G
Frog
Xenopus laevis
NP_001080593
503
57142
T373
T
A
D
I
I
L
S
T
L
Q
N
I
S
E
G
Zebra Danio
Brachydanio rerio
NP_956193
482
54628
T352
T
A
D
I
I
L
S
T
L
Q
N
I
T
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650586
481
53779
T349
A
A
D
A
A
L
L
T
L
L
N
I
S
Q
G
Honey Bee
Apis mellifera
XP_393961
485
54825
T355
S
G
D
V
I
L
M
T
L
Q
N
I
T
E
G
Nematode Worm
Caenorhab. elegans
Q21774
478
53550
T350
T
A
E
A
L
L
T
T
L
Q
N
I
F
E
G
Sea Urchin
Strong. purpuratus
XP_798221
493
55001
T363
T
A
D
V
L
L
S
T
L
Q
N
I
S
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05911
482
54492
T351
T
A
D
I
L
L
S
T
L
L
N
I
S
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.4
N.A.
93.5
93.1
N.A.
N.A.
82.6
78.9
75.6
N.A.
66.3
66.8
45.6
73.4
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
95.8
96
N.A.
N.A.
90.7
88.6
87.1
N.A.
79.9
81.4
63.2
85.4
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
86.6
N.A.
N.A.
86.6
86.6
80
N.A.
60
66.6
66.6
80
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
66.6
80
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
92
0
25
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
84
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
34
67
0
0
0
0
0
0
92
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
25
100
9
0
100
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
25
0
0
0
100
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
84
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
42
0
0
0
0
0
75
9
0
% S
% Thr:
84
0
0
25
0
0
17
100
0
0
0
0
17
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _