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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSL
All Species:
20
Human Site:
Y13
Identified Species:
40
UniProt:
P30566
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30566
NP_000017.1
484
54889
Y13
D
H
G
S
P
D
S
Y
R
S
P
L
A
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531727
490
55391
Y19
A
A
C
G
H
D
S
Y
C
S
P
L
A
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P54822
484
54790
Y13
D
P
G
S
A
E
S
Y
R
S
P
L
A
A
R
Rat
Rattus norvegicus
NP_001123975
484
54834
Y13
D
P
A
C
A
E
S
Y
R
S
P
L
A
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21265
485
54634
Y14
E
E
D
P
L
A
R
Y
R
S
P
L
V
S
R
Frog
Xenopus laevis
NP_001080593
503
57142
Y32
G
P
E
E
V
M
R
Y
R
S
P
L
V
S
R
Zebra Danio
Brachydanio rerio
NP_956193
482
54628
K22
L
V
S
R
Y
A
S
K
E
M
A
Y
N
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650586
481
53779
R15
Y
K
S
P
L
S
T
R
Y
A
S
K
E
M
Q
Honey Bee
Apis mellifera
XP_393961
485
54825
Y14
E
N
S
E
Y
S
D
Y
R
S
P
L
A
T
R
Nematode Worm
Caenorhab. elegans
Q21774
478
53550
K17
V
L
S
T
R
Y
C
K
N
S
P
L
V
S
I
Sea Urchin
Strong. purpuratus
XP_798221
493
55001
Y22
K
N
A
D
M
Y
K
Y
R
S
P
L
V
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05911
482
54492
A22
Y
A
S
K
E
M
S
A
T
F
S
L
R
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.4
N.A.
93.5
93.1
N.A.
N.A.
82.6
78.9
75.6
N.A.
66.3
66.8
45.6
73.4
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
95.8
96
N.A.
N.A.
90.7
88.6
87.1
N.A.
79.9
81.4
63.2
85.4
P-Site Identity:
100
N.A.
N.A.
60
N.A.
73.3
60
N.A.
N.A.
46.6
46.6
6.6
N.A.
0
46.6
26.6
46.6
P-Site Similarity:
100
N.A.
N.A.
60
N.A.
86.6
73.3
N.A.
N.A.
53.3
46.6
6.6
N.A.
20
66.6
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
0
17
17
0
9
0
9
9
0
42
17
0
% A
% Cys:
0
0
9
9
0
0
9
0
9
0
0
0
0
0
0
% C
% Asp:
25
0
9
9
0
17
9
0
0
0
0
0
0
0
0
% D
% Glu:
17
9
9
17
9
17
0
0
9
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% F
% Gly:
9
0
17
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
9
9
0
9
0
0
9
17
0
0
0
9
0
0
0
% K
% Leu:
9
9
0
0
17
0
0
0
0
0
0
84
0
0
0
% L
% Met:
0
0
0
0
9
17
0
0
0
9
0
0
0
9
0
% M
% Asn:
0
17
0
0
0
0
0
0
9
0
0
0
9
9
0
% N
% Pro:
0
25
0
17
9
0
0
0
0
0
75
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
9
9
0
17
9
59
0
0
0
9
0
75
% R
% Ser:
0
0
42
17
0
17
50
0
0
75
17
0
0
50
9
% S
% Thr:
0
0
0
9
0
0
9
0
9
0
0
0
0
9
0
% T
% Val:
9
9
0
0
9
0
0
0
0
0
0
0
34
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
17
17
0
67
9
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _