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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSL
All Species:
27.88
Human Site:
Y21
Identified Species:
55.76
UniProt:
P30566
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30566
NP_000017.1
484
54889
Y21
R
S
P
L
A
S
R
Y
A
S
P
E
M
C
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531727
490
55391
Y27
C
S
P
L
A
S
R
Y
A
S
P
E
M
C
F
Cat
Felis silvestris
Mouse
Mus musculus
P54822
484
54790
Y21
R
S
P
L
A
A
R
Y
A
S
R
E
M
C
F
Rat
Rattus norvegicus
NP_001123975
484
54834
Y21
R
S
P
L
A
A
R
Y
A
S
H
E
M
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21265
485
54634
Y22
R
S
P
L
V
S
R
Y
A
S
A
E
M
G
F
Frog
Xenopus laevis
NP_001080593
503
57142
Y40
R
S
P
L
V
S
R
Y
A
S
R
E
M
A
F
Zebra Danio
Brachydanio rerio
NP_956193
482
54628
D30
E
M
A
Y
N
F
S
D
R
K
K
F
T
T
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650586
481
53779
F23
Y
A
S
K
E
M
Q
F
L
F
S
D
Q
N
K
Honey Bee
Apis mellifera
XP_393961
485
54825
Y22
R
S
P
L
A
T
R
Y
A
S
K
E
M
R
Y
Nematode Worm
Caenorhab. elegans
Q21774
478
53550
L25
N
S
P
L
V
S
I
L
S
E
T
N
K
A
T
Sea Urchin
Strong. purpuratus
XP_798221
493
55001
Y30
R
S
P
L
V
S
R
Y
A
S
P
E
M
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05911
482
54492
F30
T
F
S
L
R
N
R
F
S
T
W
R
K
L
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.4
N.A.
93.5
93.1
N.A.
N.A.
82.6
78.9
75.6
N.A.
66.3
66.8
45.6
73.4
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
95.8
96
N.A.
N.A.
90.7
88.6
87.1
N.A.
79.9
81.4
63.2
85.4
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
80
0
N.A.
0
73.3
26.6
80
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
80
6.6
N.A.
26.6
86.6
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
42
17
0
0
67
0
9
0
0
25
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% D
% Glu:
9
0
0
0
9
0
0
0
0
9
0
67
0
0
0
% E
% Phe:
0
9
0
0
0
9
0
17
0
9
0
9
0
0
50
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
9
17
0
17
0
9
% K
% Leu:
0
0
0
84
0
0
0
9
9
0
0
0
0
9
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
0
0
67
0
0
% M
% Asn:
9
0
0
0
9
9
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
0
75
0
0
0
0
0
0
0
25
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% Q
% Arg:
59
0
0
0
9
0
75
0
9
0
17
9
0
9
0
% R
% Ser:
0
75
17
0
0
50
9
0
17
67
9
0
0
0
0
% S
% Thr:
9
0
0
0
0
9
0
0
0
9
9
0
9
9
9
% T
% Val:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% W
% Tyr:
9
0
0
9
0
0
0
67
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _