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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSL
All Species:
48.48
Human Site:
Y243
Identified Species:
96.97
UniProt:
P30566
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30566
NP_000017.1
484
54889
Y243
F
I
I
T
G
Q
T
Y
T
R
K
V
D
I
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531727
490
55391
Y249
F
I
I
T
G
Q
T
Y
T
R
K
V
D
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P54822
484
54790
Y243
F
I
I
T
G
Q
T
Y
T
R
K
V
D
I
E
Rat
Rattus norvegicus
NP_001123975
484
54834
Y243
Y
I
I
T
G
Q
T
Y
T
R
K
V
D
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21265
485
54634
Y244
Y
M
V
T
G
Q
T
Y
S
R
K
V
D
I
E
Frog
Xenopus laevis
NP_001080593
503
57142
Y262
Y
I
V
T
G
Q
T
Y
S
R
K
V
D
V
E
Zebra Danio
Brachydanio rerio
NP_956193
482
54628
Y241
Y
L
V
T
G
Q
T
Y
S
R
K
V
D
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650586
481
53779
Y238
Y
A
V
T
G
Q
T
Y
S
R
K
V
D
V
E
Honey Bee
Apis mellifera
XP_393961
485
54825
Y244
Y
P
V
T
G
Q
T
Y
S
R
K
V
D
V
E
Nematode Worm
Caenorhab. elegans
Q21774
478
53550
Y239
F
L
I
T
G
Q
T
Y
S
R
Q
Q
D
S
Q
Sea Urchin
Strong. purpuratus
XP_798221
493
55001
Y252
Y
M
V
T
G
Q
T
Y
S
R
K
I
D
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05911
482
54492
Y240
Y
P
V
T
G
Q
T
Y
S
R
K
I
D
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.4
N.A.
93.5
93.1
N.A.
N.A.
82.6
78.9
75.6
N.A.
66.3
66.8
45.6
73.4
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
95.8
96
N.A.
N.A.
90.7
88.6
87.1
N.A.
79.9
81.4
63.2
85.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
93.3
N.A.
N.A.
73.3
73.3
66.6
N.A.
66.6
66.6
60
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
93.3
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
25
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% E
% Phe:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
42
42
0
0
0
0
0
0
0
0
17
0
59
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% K
% Leu:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
100
0
0
0
0
9
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
67
0
0
0
0
9
0
% S
% Thr:
0
0
0
100
0
0
100
0
34
0
0
0
0
0
0
% T
% Val:
0
0
59
0
0
0
0
0
0
0
0
75
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _