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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSL
All Species:
31.82
Human Site:
Y432
Identified Species:
63.64
UniProt:
P30566
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30566
NP_000017.1
484
54889
Y432
E
R
I
Q
V
D
A
Y
F
S
P
I
H
S
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531727
490
55391
Y438
E
R
I
Q
A
D
A
Y
F
S
P
I
H
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P54822
484
54790
Y432
E
R
I
R
A
D
A
Y
F
S
P
I
H
S
Q
Rat
Rattus norvegicus
NP_001123975
484
54834
Y432
E
R
I
R
A
D
A
Y
F
S
P
I
H
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21265
485
54634
Y433
A
R
V
R
A
D
P
Y
F
S
P
I
H
E
H
Frog
Xenopus laevis
NP_001080593
503
57142
Y451
F
R
I
Q
S
D
S
Y
F
A
P
I
H
A
H
Zebra Danio
Brachydanio rerio
NP_956193
482
54628
Y430
A
R
V
Q
A
D
P
Y
F
A
P
I
L
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650586
481
53779
Y427
V
R
V
R
K
D
P
Y
F
S
P
I
L
E
Q
Honey Bee
Apis mellifera
XP_393961
485
54825
Y433
E
R
I
K
K
D
P
Y
F
K
P
I
L
D
Q
Nematode Worm
Caenorhab. elegans
Q21774
478
53550
F426
Q
T
M
A
D
P
F
F
D
S
V
R
D
R
V
Sea Urchin
Strong. purpuratus
XP_798221
493
55001
Y441
A
R
V
R
G
S
A
Y
F
A
P
I
H
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05911
482
54492
F429
E
R
V
K
R
D
E
F
F
K
P
I
W
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.4
N.A.
93.5
93.1
N.A.
N.A.
82.6
78.9
75.6
N.A.
66.3
66.8
45.6
73.4
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
95.8
96
N.A.
N.A.
90.7
88.6
87.1
N.A.
79.9
81.4
63.2
85.4
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
53.3
60
46.6
N.A.
53.3
60
6.6
53.3
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
80
66.6
N.A.
66.6
66.6
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
9
42
0
42
0
0
25
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
84
0
0
9
0
0
0
9
17
0
% D
% Glu:
50
0
0
0
0
0
9
0
0
0
0
0
0
25
17
% E
% Phe:
9
0
0
0
0
0
9
17
92
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
59
0
17
% H
% Ile:
0
0
50
0
0
0
0
0
0
0
0
92
0
0
0
% I
% Lys:
0
0
0
17
17
0
0
0
0
17
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
34
0
0
0
92
0
0
0
0
% P
% Gln:
9
0
0
34
0
0
0
0
0
0
0
0
0
0
59
% Q
% Arg:
0
92
0
42
9
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
0
0
0
0
9
9
9
0
0
59
0
0
0
34
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
42
0
9
0
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _