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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADSL
All Species:
8.79
Human Site:
Y466
Identified Species:
17.58
UniProt:
P30566
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30566
NP_000017.1
484
54889
Y466
R
F
L
E
E
E
V
Y
P
L
L
K
P
Y
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531727
490
55391
Y472
R
F
L
E
E
E
V
Y
P
L
L
K
P
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
P54822
484
54790
R466
R
F
L
E
E
E
V
R
P
L
L
K
P
Y
G
Rat
Rattus norvegicus
NP_001123975
484
54834
Y466
R
F
L
E
E
E
V
Y
P
L
L
K
P
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21265
485
54634
R467
K
F
L
K
E
E
V
R
P
A
L
I
P
Y
Q
Frog
Xenopus laevis
NP_001080593
503
57142
I485
K
F
L
K
E
E
V
I
P
L
L
S
P
Y
Q
Zebra Danio
Brachydanio rerio
NP_956193
482
54628
R464
R
F
L
S
E
E
V
R
P
V
L
E
P
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650586
481
53779
E461
E
F
V
K
E
E
V
E
P
V
L
A
R
Y
S
Honey Bee
Apis mellifera
XP_393961
485
54825
Q467
E
F
L
E
E
E
V
Q
P
V
L
E
N
Y
Q
Nematode Worm
Caenorhab. elegans
Q21774
478
53550
K460
S
F
I
A
K
E
L
K
P
T
I
D
K
Y
L
Sea Urchin
Strong. purpuratus
XP_798221
493
55001
K475
N
F
L
E
A
E
V
K
P
A
L
K
P
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05911
482
54492
N463
K
F
V
Q
K
D
V
N
N
A
L
Q
P
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92.4
N.A.
93.5
93.1
N.A.
N.A.
82.6
78.9
75.6
N.A.
66.3
66.8
45.6
73.4
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
95.8
96
N.A.
N.A.
90.7
88.6
87.1
N.A.
79.9
81.4
63.2
85.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
93.3
N.A.
N.A.
60
66.6
66.6
N.A.
46.6
60
26.6
60
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
86.6
93.3
N.A.
N.A.
80
86.6
86.6
N.A.
66.6
80
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
0
25
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
17
0
0
50
75
92
0
9
0
0
0
17
0
0
17
% E
% Phe:
0
100
0
0
0
0
0
0
0
0
0
0
0
17
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
9
9
0
0
0
% I
% Lys:
25
0
0
25
17
0
0
17
0
0
0
42
9
0
9
% K
% Leu:
0
0
75
0
0
0
9
0
0
42
92
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
92
0
0
0
75
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
9
0
0
34
% Q
% Arg:
42
0
0
0
0
0
0
25
0
0
0
0
9
0
0
% R
% Ser:
9
0
0
9
0
0
0
0
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
17
0
0
0
92
0
0
25
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
0
0
0
84
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _