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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB1
All Species:
22.73
Human Site:
S322
Identified Species:
55.56
UniProt:
P30740
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30740
NP_109591.1
379
42742
S322
I
S
K
I
V
H
K
S
F
V
E
V
N
E
E
Chimpanzee
Pan troglodytes
XP_527219
508
55991
S451
I
S
K
I
V
H
K
S
F
V
E
V
N
E
E
Rhesus Macaque
Macaca mulatta
XP_001091038
379
42666
S322
I
S
K
I
V
H
K
S
F
V
E
V
N
E
E
Dog
Lupus familis
XP_545313
382
43329
F326
S
K
I
V
H
K
S
F
V
E
V
N
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D154
379
42556
S322
I
S
K
I
V
H
K
S
F
V
E
V
N
E
E
Rat
Rattus norvegicus
Q4G075
379
42708
A322
I
S
K
I
V
H
K
A
F
V
E
V
N
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505473
379
42769
S322
I
S
K
I
I
H
K
S
F
V
E
V
N
E
E
Chicken
Gallus gallus
O73790
410
47365
F350
S
K
V
I
H
Q
S
F
V
A
V
D
E
K
G
Frog
Xenopus laevis
Q52L45
377
42679
S321
L
S
E
V
I
H
K
S
F
V
E
V
N
E
E
Zebra Danio
Brachydanio rerio
NP_001002653
380
42866
K322
F
L
S
A
V
A
H
K
A
F
V
D
V
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.6
96
75.6
N.A.
80.4
81.7
N.A.
75.7
43.6
63.5
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.2
98.6
84.5
N.A.
91.2
92.3
N.A.
89.7
61.4
81
73.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
93.3
6.6
73.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
13.3
100
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
10
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
10
70
0
20
80
80
% E
% Phe:
10
0
0
0
0
0
0
20
70
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% G
% His:
0
0
0
0
20
70
10
0
0
0
0
0
0
0
0
% H
% Ile:
60
0
10
70
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
60
0
0
10
70
10
0
0
0
0
0
10
0
% K
% Leu:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
70
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
70
10
0
0
0
20
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
20
60
0
0
0
20
70
30
70
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _