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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERPINB1 All Species: 30.91
Human Site: Y199 Identified Species: 75.56
UniProt: P30740 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30740 NP_109591.1 379 42742 Y199 R K T V K M M Y Q K K K F A Y
Chimpanzee Pan troglodytes XP_527219 508 55991 Y328 R K T V K M M Y Q K K K F A Y
Rhesus Macaque Macaca mulatta XP_001091038 379 42666 Y199 T K T V K M M Y Q K K K F A Y
Dog Lupus familis XP_545313 382 43329 Y203 K K T V K M M Y K K K K F P F
Cat Felis silvestris
Mouse Mus musculus Q9D154 379 42556 Y199 T K T V K M M Y Q K K K F P F
Rat Rattus norvegicus Q4G075 379 42708 Y199 T K S V K M M Y Q K K K F F F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505473 379 42769 Y199 Q K T V R M M Y Q K K K L P Y
Chicken Gallus gallus O73790 410 47365 Y227 S K P V K M M Y M R D T F P V
Frog Xenopus laevis Q52L45 377 42679 M198 K E Q K T V K M M Y Q K E K L
Zebra Danio Brachydanio rerio NP_001002653 380 42866 Y199 N R P V Q M M Y Q K K K F P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 96 75.6 N.A. 80.4 81.7 N.A. 75.7 43.6 63.5 56.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 74.2 98.6 84.5 N.A. 91.2 92.3 N.A. 89.7 61.4 81 73.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 80 73.3 N.A. 73.3 46.6 6.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 86.6 53.3 33.3 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 80 10 40 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 20 80 0 10 70 0 10 0 10 80 80 90 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % L
% Met: 0 0 0 0 0 90 90 10 20 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 0 0 0 0 0 0 0 0 0 0 50 0 % P
% Gln: 10 0 10 0 10 0 0 0 70 0 10 0 0 0 0 % Q
% Arg: 20 10 0 0 10 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 30 0 60 0 10 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 90 0 10 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 90 0 10 0 0 0 0 40 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _