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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCH1
All Species:
50
Human Site:
S139
Identified Species:
84.62
UniProt:
P30793
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30793
NP_000152.1
250
27903
S139
V
K
D
I
D
M
F
S
M
C
E
H
H
L
V
Chimpanzee
Pan troglodytes
XP_001161531
209
23113
A101
T
P
W
R
A
A
S
A
M
Q
F
F
T
K
G
Rhesus Macaque
Macaca mulatta
XP_001087365
250
27907
S139
V
K
D
I
D
M
F
S
M
C
E
H
H
L
V
Dog
Lupus familis
XP_851883
249
27613
S138
V
K
D
I
D
M
F
S
M
C
E
H
H
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q05915
241
26996
S130
V
K
D
I
D
M
F
S
M
C
E
H
H
L
V
Rat
Rattus norvegicus
P22288
241
27039
S130
V
K
D
I
D
M
F
S
M
C
E
H
H
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P50141
236
26096
S125
V
K
N
I
D
M
F
S
L
C
E
H
H
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571742
240
27026
S127
V
K
D
I
D
M
F
S
L
C
E
H
H
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48596
324
35523
S212
V
K
D
I
E
M
F
S
M
C
E
H
H
L
V
Honey Bee
Apis mellifera
XP_393086
269
30401
S157
V
K
D
I
E
M
F
S
M
C
E
H
H
L
V
Nematode Worm
Caenorhab. elegans
Q19980
223
25114
E114
I
E
M
F
S
L
C
E
H
H
L
V
P
F
M
Sea Urchin
Strong. purpuratus
XP_788725
273
30337
S162
V
K
D
I
E
M
F
S
L
C
E
H
H
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P51601
243
27751
S130
V
R
D
I
E
I
Y
S
L
C
E
H
H
L
V
Red Bread Mold
Neurospora crassa
P51599
313
34453
S200
V
K
D
I
E
V
F
S
M
C
E
H
H
L
V
Conservation
Percent
Protein Identity:
100
83.5
98.8
96.4
N.A.
86
89.1
N.A.
N.A.
80
N.A.
65.5
N.A.
51.5
56.1
58.4
56.4
Protein Similarity:
100
83.5
98.8
98.4
N.A.
90.4
92
N.A.
N.A.
87.1
N.A.
74.4
N.A.
61.7
66.5
72.4
67.4
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
93.3
N.A.
93.3
93.3
0
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
100
100
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
52.8
45.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.6
57.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
100
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
86
0
0
0
0
0
% C
% Asp:
0
0
79
0
50
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
36
0
0
8
0
0
86
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
79
0
0
0
8
8
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
86
86
0
0
% H
% Ile:
8
0
0
86
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
79
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
8
0
0
29
0
8
0
0
86
0
% L
% Met:
0
0
8
0
0
72
0
0
65
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
8
86
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
86
0
0
0
0
8
0
0
0
0
0
8
0
0
86
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _