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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCH1
All Species:
48.18
Human Site:
T225
Identified Species:
81.54
UniProt:
P30793
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30793
NP_000152.1
250
27903
T225
V
Q
K
M
N
S
K
T
V
T
S
T
M
L
G
Chimpanzee
Pan troglodytes
XP_001161531
209
23113
L185
R
L
Q
V
Q
E
R
L
T
K
Q
I
A
V
A
Rhesus Macaque
Macaca mulatta
XP_001087365
250
27907
T225
V
Q
K
M
N
S
K
T
V
T
S
T
M
L
G
Dog
Lupus familis
XP_851883
249
27613
T224
V
Q
K
M
N
S
K
T
V
T
S
T
M
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q05915
241
26996
T216
V
Q
K
M
N
S
K
T
V
T
S
T
M
L
G
Rat
Rattus norvegicus
P22288
241
27039
T216
V
Q
K
M
N
S
K
T
V
T
S
T
M
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P50141
236
26096
T211
V
Q
K
M
N
S
K
T
A
T
S
T
M
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571742
240
27026
T213
V
Q
K
M
N
S
R
T
V
T
S
A
M
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48596
324
35523
T298
V
Q
K
I
N
S
K
T
V
T
S
T
M
L
G
Honey Bee
Apis mellifera
XP_393086
269
30401
T243
V
Q
K
I
N
S
K
T
V
T
S
T
M
L
G
Nematode Worm
Caenorhab. elegans
Q19980
223
25114
T198
Q
K
I
N
A
S
T
T
T
S
C
M
L
G
V
Sea Urchin
Strong. purpuratus
XP_788725
273
30337
T248
V
Q
K
L
N
S
K
T
I
T
S
C
M
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P51601
243
27751
T216
I
Q
K
T
G
S
S
T
V
T
S
C
M
L
G
Red Bread Mold
Neurospora crassa
P51599
313
34453
T286
V
Q
K
T
T
S
S
T
I
T
S
C
V
L
G
Conservation
Percent
Protein Identity:
100
83.5
98.8
96.4
N.A.
86
89.1
N.A.
N.A.
80
N.A.
65.5
N.A.
51.5
56.1
58.4
56.4
Protein Similarity:
100
83.5
98.8
98.4
N.A.
90.4
92
N.A.
N.A.
87.1
N.A.
74.4
N.A.
61.7
66.5
72.4
67.4
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
93.3
93.3
13.3
80
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
100
100
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
52.8
45.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.6
57.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
22
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
86
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
15
0
0
0
0
15
0
0
8
0
0
0
% I
% Lys:
0
8
86
0
0
0
65
0
0
8
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
0
0
8
0
0
0
0
8
86
0
% L
% Met:
0
0
0
50
0
0
0
0
0
0
0
8
79
0
0
% M
% Asn:
0
0
0
8
72
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
86
8
0
8
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
93
15
0
0
8
86
0
0
0
0
% S
% Thr:
0
0
0
15
8
0
8
93
15
86
0
58
0
0
0
% T
% Val:
79
0
0
8
0
0
0
0
65
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _