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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCH1
All Species:
34.55
Human Site:
T94
Identified Species:
58.46
UniProt:
P30793
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30793
NP_000152.1
250
27903
T94
Q
R
Q
G
L
L
K
T
P
W
R
A
A
S
A
Chimpanzee
Pan troglodytes
XP_001161531
209
23113
L66
R
S
E
E
D
N
E
L
N
L
P
N
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001087365
250
27907
T94
Q
R
Q
G
L
L
K
T
P
W
R
A
A
S
A
Dog
Lupus familis
XP_851883
249
27613
T93
Q
R
Q
G
L
L
K
T
P
W
R
A
A
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q05915
241
26996
T85
Q
R
Q
G
L
L
K
T
P
W
R
A
A
T
A
Rat
Rattus norvegicus
P22288
241
27039
T85
Q
R
Q
G
L
L
K
T
P
W
R
A
A
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P50141
236
26096
R83
G
L
L
K
T
P
W
R
A
A
T
A
M
Q
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571742
240
27026
A86
L
L
K
T
P
L
R
A
A
K
A
M
Q
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48596
324
35523
T167
D
R
Q
G
L
I
K
T
P
E
R
A
A
K
A
Honey Bee
Apis mellifera
XP_393086
269
30401
T112
N
R
P
G
L
L
K
T
P
E
R
A
A
K
A
Nematode Worm
Caenorhab. elegans
Q19980
223
25114
K79
K
A
M
M
A
F
T
K
G
Y
D
D
Q
L
D
Sea Urchin
Strong. purpuratus
XP_788725
273
30337
T117
N
R
Q
G
L
K
K
T
P
D
R
A
A
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P51601
243
27751
T84
N
R
E
G
L
L
D
T
P
Q
R
Y
A
K
A
Red Bread Mold
Neurospora crassa
P51599
313
34453
T155
D
R
E
G
L
L
A
T
P
E
R
Y
A
K
A
Conservation
Percent
Protein Identity:
100
83.5
98.8
96.4
N.A.
86
89.1
N.A.
N.A.
80
N.A.
65.5
N.A.
51.5
56.1
58.4
56.4
Protein Similarity:
100
83.5
98.8
98.4
N.A.
90.4
92
N.A.
N.A.
87.1
N.A.
74.4
N.A.
61.7
66.5
72.4
67.4
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
73.3
73.3
0
73.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
20
N.A.
80
73.3
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
52.8
45.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.6
57.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
8
15
8
8
65
72
8
79
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
8
0
8
0
0
8
8
8
0
0
8
% D
% Glu:
0
0
22
8
0
0
8
0
0
22
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
8
0
0
72
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
8
0
8
58
8
0
8
0
0
0
36
0
% K
% Leu:
8
15
8
0
72
65
0
8
0
8
0
0
8
8
8
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
22
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
8
0
8
8
0
0
72
0
8
0
0
0
0
% P
% Gln:
36
0
50
0
0
0
0
0
0
8
0
0
15
8
0
% Q
% Arg:
8
72
0
0
0
0
8
8
0
0
72
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
0
0
0
15
0
% S
% Thr:
0
0
0
8
8
0
8
72
0
0
8
0
0
22
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
36
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _