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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1B1
All Species:
41.52
Human Site:
T53
Identified Species:
70.26
UniProt:
P30837
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30837
NP_000683.3
517
57238
T53
Q
D
A
V
S
K
K
T
F
P
T
V
N
P
T
Chimpanzee
Pan troglodytes
XP_001170537
517
57258
T53
Q
D
A
V
S
K
K
T
F
P
T
V
N
P
T
Rhesus Macaque
Macaca mulatta
XP_001114412
517
57157
T53
Q
D
A
V
S
K
K
T
F
P
T
V
N
P
T
Dog
Lupus familis
XP_538742
520
57674
T56
Q
D
A
A
S
K
K
T
F
P
T
V
N
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZS1
519
57534
T55
H
D
A
V
S
K
K
T
F
P
T
V
N
P
T
Rat
Rattus norvegicus
Q66HF8
519
57606
T55
H
D
A
V
S
K
K
T
F
P
T
V
N
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519422
517
57648
T53
R
D
A
V
S
K
K
T
F
P
T
V
N
P
S
Chicken
Gallus gallus
P27463
509
55791
K56
F
N
P
A
N
E
E
K
I
C
E
V
A
E
G
Frog
Xenopus laevis
NP_001087022
521
57231
T57
H
D
A
V
S
K
K
T
F
P
T
I
N
P
S
Zebra Danio
Brachydanio rerio
NP_998466
516
56531
T52
H
D
A
V
S
K
K
T
F
P
T
I
N
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609285
520
57001
I56
H
K
S
K
S
G
K
I
F
E
T
I
N
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786787
525
56894
T61
V
N
S
V
S
G
K
T
F
P
T
I
N
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
T74
V
D
S
A
S
G
K
T
F
P
T
L
D
P
R
Baker's Yeast
Sacchar. cerevisiae
P32872
511
56448
I57
H
N
L
V
L
E
K
I
F
P
V
Y
N
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
94.4
N.A.
94
93.6
N.A.
90.1
65.7
70
69.6
N.A.
66.5
N.A.
N.A.
64.5
Protein Similarity:
100
99.6
98.8
97.8
N.A.
96.7
97.1
N.A.
95.5
78.3
83.6
84.9
N.A.
80.3
N.A.
N.A.
81.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
6.6
80
80
N.A.
46.6
N.A.
N.A.
60
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
33.3
93.3
86.6
N.A.
60
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
54
53.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
66.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
65
22
0
0
0
0
0
0
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
72
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
15
8
0
0
8
8
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
8
% G
% His:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
8
0
0
29
0
0
0
% I
% Lys:
0
8
0
8
0
65
93
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
22
0
0
8
0
0
0
0
0
0
0
86
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
86
0
0
0
93
0
% P
% Gln:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
22
0
86
0
0
0
0
0
0
0
0
0
22
% S
% Thr:
0
0
0
0
0
0
0
79
0
0
86
0
0
0
50
% T
% Val:
15
0
0
72
0
0
0
0
0
0
8
58
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _