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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH3A1
All Species:
19.7
Human Site:
S446
Identified Species:
39.39
UniProt:
P30838
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30838
NP_000682.3
453
50379
S446
L
K
V
R
Y
P
P
S
P
A
K
M
T
Q
H
Chimpanzee
Pan troglodytes
XP_523577
402
44656
Rhesus Macaque
Macaca mulatta
XP_001102220
450
50099
S443
L
K
V
R
Y
P
P
S
P
A
K
M
T
W
H
Dog
Lupus familis
XP_536656
485
54244
N443
N
K
L
R
Y
P
P
N
S
Q
S
K
V
D
W
Cat
Felis silvestris
Mouse
Mus musculus
P47739
453
50448
S446
N
K
A
R
Y
P
P
S
P
A
K
M
P
R
H
Rat
Rattus norvegicus
P11883
453
50320
S446
H
K
A
R
Y
P
P
S
P
A
K
M
P
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508369
491
54456
S446
L
R
V
R
Y
P
P
S
P
L
K
V
T
P
Q
Chicken
Gallus gallus
NP_001006223
490
53992
S446
N
M
V
R
Y
P
P
S
S
Q
K
K
L
D
W
Frog
Xenopus laevis
NP_001088940
483
54130
Y443
N
K
I
R
Y
P
P
Y
S
M
K
K
V
E
W
Zebra Danio
Brachydanio rerio
XP_002666107
514
57788
H446
N
K
M
R
Y
P
P
H
T
A
D
K
L
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q70DU8
484
53140
N472
L
K
A
L
V
D
S
N
I
F
D
L
F
K
V
Baker's Yeast
Sacchar. cerevisiae
Q04458
532
59960
N482
L
F
M
R
Y
P
P
N
S
A
Q
K
E
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
96.4
62.2
N.A.
80.5
81.9
N.A.
73.7
61.6
60
52.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.7
97.7
80
N.A.
90.9
91.8
N.A.
84.3
77.5
76.1
69
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
33.3
N.A.
73.3
73.3
N.A.
66.6
46.6
40
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
93.3
46.6
N.A.
80
80
N.A.
80
46.6
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
17
0
0
17
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
34
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
67
0
0
0
0
0
0
0
0
59
42
0
17
0
% K
% Leu:
42
0
9
9
0
0
0
0
0
9
0
9
17
0
9
% L
% Met:
0
9
17
0
0
0
0
0
0
9
0
34
0
0
0
% M
% Asn:
42
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
84
84
0
42
0
0
0
17
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
17
9
0
0
9
9
% Q
% Arg:
0
9
0
84
0
0
0
0
0
0
0
0
0
17
0
% R
% Ser:
0
0
0
0
0
0
9
50
34
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
25
0
0
% T
% Val:
0
0
34
0
9
0
0
0
0
0
0
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
34
% W
% Tyr:
0
0
0
0
84
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _