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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH3A1 All Species: 12.42
Human Site: Y73 Identified Species: 24.85
UniProt: P30838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30838 NP_000682.3 453 50379 Y73 Y V L E E I E Y M I Q K L P E
Chimpanzee Pan troglodytes XP_523577 402 44656 L47 P Q T Q Q D E L Y I H S E P L
Rhesus Macaque Macaca mulatta XP_001102220 450 50099 Y70 Y V L E E I E Y M I Q K L P E
Dog Lupus familis XP_536656 485 54244 L70 T V L G E L D L V L E N L P E
Cat Felis silvestris
Mouse Mus musculus P47739 453 50448 F73 H V L D E I D F T I K G L S D
Rat Rattus norvegicus P11883 453 50320 T73 H V L E E L D T T I K E L P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508369 491 54456 Y73 Y S L E E I D Y A L Q K L P E
Chicken Gallus gallus NP_001006223 490 53992 L73 G V L G E L A L A M E K L P S
Frog Xenopus laevis NP_001088940 483 54130 L70 G M L G E I D L A I E N L P K
Zebra Danio Brachydanio rerio XP_002666107 514 57788 L73 G V E S E I N L A L K K L K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q70DU8 484 53140 L81 L L R N S I K L A L K Q L K N
Baker's Yeast Sacchar. cerevisiae Q04458 532 59960 H96 K L M N D I L H L I E I L P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 96.4 62.2 N.A. 80.5 81.9 N.A. 73.7 61.6 60 52.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.7 97.7 80 N.A. 90.9 91.8 N.A. 84.3 77.5 76.1 69 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 40 N.A. 40 46.6 N.A. 73.3 40 40 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 73.3 N.A. 80 86.6 N.A. 86.6 60 66.6 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.1 48.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 42 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 9 9 42 0 0 0 0 0 0 0 17 % D
% Glu: 0 0 9 34 75 0 25 0 0 0 34 9 9 0 42 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 25 0 0 25 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 17 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 67 0 0 0 59 0 9 0 0 0 % I
% Lys: 9 0 0 0 0 0 9 0 0 0 34 42 0 17 17 % K
% Leu: 9 17 67 0 0 25 9 50 9 34 0 0 92 0 9 % L
% Met: 0 9 9 0 0 0 0 0 17 9 0 0 0 0 0 % M
% Asn: 0 0 0 17 0 0 9 0 0 0 0 17 0 0 9 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % P
% Gln: 0 9 0 9 9 0 0 0 0 0 25 9 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 9 9 0 0 0 0 0 0 9 0 9 9 % S
% Thr: 9 0 9 0 0 0 0 9 17 0 0 0 0 0 0 % T
% Val: 0 59 0 0 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 25 0 0 0 0 0 0 25 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _