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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH3A1 All Species: 29.39
Human Site: Y99 Identified Species: 58.79
UniProt: P30838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30838 NP_000682.3 453 50379 Y99 Q T Q Q D E L Y I H S E P L G
Chimpanzee Pan troglodytes XP_523577 402 44656 I71 N Y P F N L T I Q P M V G A I
Rhesus Macaque Macaca mulatta XP_001102220 450 50099 Y96 Q T Q Q D E L Y I H S E P L G
Dog Lupus familis XP_536656 485 54244 Y96 L T M L D E A Y V Q P E P L G
Cat Felis silvestris
Mouse Mus musculus P47739 453 50448 Y99 Q T Q E D D L Y I H S E P L G
Rat Rattus norvegicus P11883 453 50320 Y99 Q T Q Q D D L Y I H S E P L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508369 491 54456 Y99 L S A D D E T Y I H S E P L G
Chicken Gallus gallus NP_001006223 490 53992 Y99 L T L R D E A Y I N P E P L G
Frog Xenopus laevis NP_001088940 483 54130 Y96 M T M G D D V Y I N Y E P L G
Zebra Danio Brachydanio rerio XP_002666107 514 57788 Y99 M T I S D Q V Y I Q P E P L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q70DU8 484 53140 E107 T T F P A S A E I V S E P L G
Baker's Yeast Sacchar. cerevisiae Q04458 532 59960 I123 P F M F G K T I V E K I S R G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 96.4 62.2 N.A. 80.5 81.9 N.A. 73.7 61.6 60 52.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.7 97.7 80 N.A. 90.9 91.8 N.A. 84.3 77.5 76.1 69 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 53.3 N.A. 86.6 93.3 N.A. 66.6 60 53.3 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 60 N.A. 100 100 N.A. 73.3 73.3 73.3 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.1 48.8 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 0 25 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 75 25 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 42 0 9 0 9 0 84 0 0 0 % E
% Phe: 0 9 9 17 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 0 0 0 0 0 0 0 9 0 92 % G
% His: 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 17 75 0 0 9 0 0 9 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % K
% Leu: 25 0 9 9 0 9 34 0 0 0 0 0 0 84 0 % L
% Met: 17 0 25 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 9 0 0 0 9 0 0 0 0 17 0 0 0 0 0 % N
% Pro: 9 0 9 9 0 0 0 0 0 9 25 0 84 0 0 % P
% Gln: 34 0 34 25 0 9 0 0 9 17 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 9 0 9 0 9 0 0 0 0 50 0 9 0 0 % S
% Thr: 9 75 0 0 0 0 25 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 17 0 17 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 75 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _