KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2B
All Species:
36.67
Human Site:
S893
Identified Species:
67.22
UniProt:
P30876
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30876
NP_000929.1
1174
133897
S893
R
Y
T
K
R
D
C
S
T
F
L
R
T
S
E
Chimpanzee
Pan troglodytes
XP_001136218
1099
125171
Q831
S
E
T
G
I
V
D
Q
V
M
V
T
L
N
Q
Rhesus Macaque
Macaca mulatta
XP_001083325
1235
140431
S954
R
Y
T
K
R
D
C
S
T
F
L
R
T
S
E
Dog
Lupus familis
XP_861018
1173
133745
S892
R
Y
T
K
R
D
C
S
T
F
L
R
T
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI7
1174
133892
S893
R
Y
T
K
R
D
C
S
T
F
L
R
T
S
E
Rat
Rattus norvegicus
O54888
1135
127691
S861
V
C
S
N
D
T
G
S
G
K
F
K
C
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006448
1174
133860
S893
R
F
T
K
R
D
C
S
T
F
L
R
T
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019632
1174
133813
S893
R
Y
T
K
R
D
C
S
T
F
L
R
T
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08266
1176
134024
S895
R
F
S
K
R
D
A
S
T
F
L
R
N
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
S899
K
Y
P
K
R
D
A
S
T
F
L
R
S
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
S901
T
R
R
D
H
S
I
S
L
R
H
S
E
T
G
Baker's Yeast
Sacchar. cerevisiae
P08518
1224
138733
S938
Y
H
S
K
R
D
A
S
T
P
L
R
S
T
E
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y890
G
V
T
H
Y
E
R
Y
K
D
S
E
D
A
F
Conservation
Percent
Protein Identity:
100
93.4
95
99.6
N.A.
99.9
26.9
N.A.
N.A.
99.4
N.A.
97
N.A.
85.9
N.A.
77.8
N.A.
Protein Similarity:
100
93.6
95
99.7
N.A.
100
43.4
N.A.
N.A.
99.8
N.A.
99.3
N.A.
94
N.A.
88.8
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
N.A.
93.3
N.A.
100
N.A.
73.3
N.A.
73.3
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
20
N.A.
N.A.
100
N.A.
100
N.A.
86.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
66.6
58.7
26.4
Protein Similarity:
N.A.
N.A.
N.A.
80.1
74.2
44.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
80
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
24
0
0
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
47
0
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
8
8
70
8
0
0
8
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
0
0
0
8
8
0
70
% E
% Phe:
0
16
0
0
0
0
0
0
0
62
8
0
0
0
8
% F
% Gly:
8
0
0
8
0
0
8
0
8
0
0
0
0
0
8
% G
% His:
0
8
0
8
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
70
0
0
0
0
8
8
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
70
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
54
8
8
0
70
0
8
0
0
8
0
70
0
0
0
% R
% Ser:
8
0
24
0
0
8
0
85
0
0
8
8
16
62
0
% S
% Thr:
8
0
62
0
0
8
0
0
70
0
0
8
47
16
0
% T
% Val:
8
8
0
0
0
8
0
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
47
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _