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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2B
All Species:
28.79
Human Site:
T147
Identified Species:
52.78
UniProt:
P30876
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30876
NP_000929.1
1174
133897
T147
L
Q
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Chimpanzee
Pan troglodytes
XP_001136218
1099
125171
T143
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
L
Rhesus Macaque
Macaca mulatta
XP_001083325
1235
140431
T208
L
Q
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Dog
Lupus familis
XP_861018
1173
133745
T147
L
Q
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI7
1174
133892
T147
L
Q
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Rat
Rattus norvegicus
O54888
1135
127691
N150
S
K
L
C
N
L
Y
N
L
P
P
Q
V
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006448
1174
133860
T147
L
Q
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019632
1174
133813
T147
Q
Q
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08266
1176
134024
T148
V
E
T
Q
H
Q
K
T
F
I
G
K
I
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
F154
E
K
V
Y
D
K
V
F
V
G
K
V
P
V
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
D149
E
E
V
T
E
T
Q
D
F
T
K
V
F
I
G
Baker's Yeast
Sacchar. cerevisiae
P08518
1224
138733
L151
G
R
E
L
K
Y
E
L
I
A
E
E
S
E
D
Red Bread Mold
Neurospora crassa
O74633
1234
138583
M155
F
V
R
E
L
G
Q
M
P
I
M
V
K
S
N
Conservation
Percent
Protein Identity:
100
93.4
95
99.6
N.A.
99.9
26.9
N.A.
N.A.
99.4
N.A.
97
N.A.
85.9
N.A.
77.8
N.A.
Protein Similarity:
100
93.6
95
99.7
N.A.
100
43.4
N.A.
N.A.
99.8
N.A.
99.3
N.A.
94
N.A.
88.8
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
N.A.
100
N.A.
93.3
N.A.
86.6
N.A.
0
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
33.3
N.A.
N.A.
100
N.A.
93.3
N.A.
100
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
66.6
58.7
26.4
Protein Similarity:
N.A.
N.A.
N.A.
80.1
74.2
44.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
16
16
8
8
8
0
8
0
0
8
8
8
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
8
62
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
8
8
54
0
0
0
8
% G
% His:
0
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
62
0
0
54
8
62
% I
% Lys:
8
16
0
8
8
8
54
0
0
0
16
54
8
0
0
% K
% Leu:
39
0
8
8
8
8
0
8
8
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
8
8
0
8
54
0
% P
% Gln:
8
47
0
54
0
54
16
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
0
0
0
0
0
16
8
0
% S
% Thr:
0
0
54
8
0
8
0
62
0
8
0
0
0
0
0
% T
% Val:
8
8
16
0
0
0
8
0
8
0
0
24
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
8
16
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _