KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2B
All Species:
24.24
Human Site:
Y217
Identified Species:
44.44
UniProt:
P30876
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30876
NP_000929.1
1174
133897
Y217
K
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
Chimpanzee
Pan troglodytes
XP_001136218
1099
125171
H212
S
D
R
D
I
L
E
H
I
I
Y
D
F
E
D
Rhesus Macaque
Macaca mulatta
XP_001083325
1235
140431
Y278
K
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
Dog
Lupus familis
XP_861018
1173
133745
Y217
K
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI7
1174
133892
Y217
K
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
Rat
Rattus norvegicus
O54888
1135
127691
A221
C
V
R
E
E
H
S
A
V
N
M
N
L
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006448
1174
133860
Y217
K
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019632
1174
133813
Y217
K
K
D
S
K
Y
A
Y
T
G
E
C
R
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08266
1176
134024
F218
M
K
D
G
K
Y
A
F
K
T
E
I
R
S
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
F223
M
K
D
G
K
Y
A
F
K
T
E
C
R
S
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
A223
K
R
Q
P
N
K
Y
A
Y
V
G
E
V
R
S
Baker's Yeast
Sacchar. cerevisiae
P08518
1224
138733
A230
V
Q
V
F
K
K
A
A
P
S
P
I
S
H
V
Red Bread Mold
Neurospora crassa
O74633
1234
138583
Y223
F
Q
N
R
G
A
S
Y
T
P
Y
G
I
I
M
Conservation
Percent
Protein Identity:
100
93.4
95
99.6
N.A.
99.9
26.9
N.A.
N.A.
99.4
N.A.
97
N.A.
85.9
N.A.
77.8
N.A.
Protein Similarity:
100
93.6
95
99.7
N.A.
100
43.4
N.A.
N.A.
99.8
N.A.
99.3
N.A.
94
N.A.
88.8
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
N.A.
100
N.A.
100
N.A.
60
N.A.
66.6
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
20
N.A.
N.A.
100
N.A.
100
N.A.
66.6
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
66.6
58.7
26.4
Protein Similarity:
N.A.
N.A.
N.A.
80.1
74.2
44.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
70
24
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
54
0
0
62
% C
% Asp:
0
8
62
8
0
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
8
8
0
8
0
0
0
62
8
0
8
0
% E
% Phe:
8
0
0
8
0
0
0
16
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
16
8
0
0
0
0
47
8
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
16
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
8
0
16
8
8
0
% I
% Lys:
54
62
0
0
70
16
0
0
16
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
8
0
8
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
8
8
0
0
0
0
% P
% Gln:
0
16
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
16
8
0
0
0
0
0
0
0
0
62
8
0
% R
% Ser:
8
0
0
47
0
0
16
0
0
8
0
0
8
62
8
% S
% Thr:
0
0
0
0
0
0
0
0
54
16
0
0
0
0
0
% T
% Val:
8
8
8
0
0
0
0
0
8
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
62
8
54
8
0
16
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _