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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNRHR All Species: 16.67
Human Site: S151 Identified Species: 36.67
UniProt: P30968 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30968 NP_000397.1 328 37731 S151 T R P L A L K S N S K V G Q S
Chimpanzee Pan troglodytes XP_526608 328 37738 S151 T R P L A L K S N S K L G Q S
Rhesus Macaque Macaca mulatta Q95JG1 379 41441 R153 L G S R S G V R K L L G A A W
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q01776 327 37665 S151 T Q P L A V Q S N S K L E Q S
Rat Rattus norvegicus P30969 327 37729 S151 T Q P L A V Q S K S K L E R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001116830 332 37290 S155 T R P L A V K S L T Q L G R G
Chicken Gallus gallus NP_001012627 419 45457 R177 L R P L A I A R A R C R N R A
Frog Xenopus laevis NP_001079176 368 41711 C184 P G V N F T Q C A T H G S F T
Zebra Danio Brachydanio rerio A0T2N3 359 40129 A153 R T R G H M R A S L T A I W L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001035354 349 40615 K151 L Q L W D V D K R G K I M L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001116990 440 49788 K179 V H P L S V S K A D R R C K I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 35.6 N.A. N.A. 89.3 87.5 N.A. 70.4 32.9 38.8 21.1 N.A. N.A. 30 N.A. 26.1
Protein Similarity: 100 100 50.4 N.A. N.A. 94.5 93.5 N.A. 81.9 49.1 56.2 39.8 N.A. N.A. 51.8 N.A. 43.6
P-Site Identity: 100 93.3 0 N.A. N.A. 66.6 53.3 N.A. 53.3 26.6 0 0 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 100 6.6 N.A. N.A. 93.3 86.6 N.A. 86.6 46.6 20 26.6 N.A. N.A. 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 55 0 10 10 28 0 0 10 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 10 0 10 0 0 % C
% Asp: 0 0 0 0 10 0 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 19 0 10 0 10 0 0 0 10 0 19 28 0 10 % G
% His: 0 10 0 0 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 10 10 0 10 % I
% Lys: 0 0 0 0 0 0 28 19 19 0 46 0 0 10 0 % K
% Leu: 28 0 10 64 0 19 0 0 10 19 10 37 0 10 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 28 0 0 0 10 0 0 % N
% Pro: 10 0 64 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 28 0 0 0 0 28 0 0 0 10 0 0 28 0 % Q
% Arg: 10 37 10 10 0 0 10 19 10 10 10 19 0 28 0 % R
% Ser: 0 0 10 0 19 0 10 46 10 37 0 0 10 0 46 % S
% Thr: 46 10 0 0 0 10 0 0 0 19 10 0 0 0 10 % T
% Val: 10 0 10 0 0 46 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _