KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNRHR
All Species:
17.27
Human Site:
S153
Identified Species:
38
UniProt:
P30968
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30968
NP_000397.1
328
37731
S153
P
L
A
L
K
S
N
S
K
V
G
Q
S
M
V
Chimpanzee
Pan troglodytes
XP_526608
328
37738
S153
P
L
A
L
K
S
N
S
K
L
G
Q
S
M
V
Rhesus Macaque
Macaca mulatta
Q95JG1
379
41441
L155
S
R
S
G
V
R
K
L
L
G
A
A
W
G
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q01776
327
37665
S153
P
L
A
V
Q
S
N
S
K
L
E
Q
S
M
I
Rat
Rattus norvegicus
P30969
327
37729
S153
P
L
A
V
Q
S
K
S
K
L
E
R
S
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001116830
332
37290
T157
P
L
A
V
K
S
L
T
Q
L
G
R
G
L
I
Chicken
Gallus gallus
NP_001012627
419
45457
R179
P
L
A
I
A
R
A
R
C
R
N
R
A
M
L
Frog
Xenopus laevis
NP_001079176
368
41711
T186
V
N
F
T
Q
C
A
T
H
G
S
F
T
Q
H
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
L155
R
G
H
M
R
A
S
L
T
A
I
W
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001035354
349
40615
G153
L
W
D
V
D
K
R
G
K
I
M
L
S
F
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116990
440
49788
D181
P
L
S
V
S
K
A
D
R
R
C
K
I
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
35.6
N.A.
N.A.
89.3
87.5
N.A.
70.4
32.9
38.8
21.1
N.A.
N.A.
30
N.A.
26.1
Protein Similarity:
100
100
50.4
N.A.
N.A.
94.5
93.5
N.A.
81.9
49.1
56.2
39.8
N.A.
N.A.
51.8
N.A.
43.6
P-Site Identity:
100
93.3
0
N.A.
N.A.
66.6
53.3
N.A.
40
26.6
0
0
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
100
13.3
N.A.
N.A.
93.3
80
N.A.
86.6
53.3
20
33.3
N.A.
N.A.
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
55
0
10
10
28
0
0
10
10
10
10
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
10
0
10
0
0
0
10
0
19
28
0
10
10
0
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
10
0
10
0
19
% I
% Lys:
0
0
0
0
28
19
19
0
46
0
0
10
0
0
0
% K
% Leu:
10
64
0
19
0
0
10
19
10
37
0
10
10
19
28
% L
% Met:
0
0
0
10
0
0
0
0
0
0
10
0
0
55
0
% M
% Asn:
0
10
0
0
0
0
28
0
0
0
10
0
0
0
0
% N
% Pro:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
28
0
0
0
10
0
0
28
0
10
0
% Q
% Arg:
10
10
0
0
10
19
10
10
10
19
0
28
0
0
0
% R
% Ser:
10
0
19
0
10
46
10
37
0
0
10
0
46
0
10
% S
% Thr:
0
0
0
10
0
0
0
19
10
0
0
0
10
0
10
% T
% Val:
10
0
0
46
10
0
0
0
0
10
0
0
0
0
19
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _