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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNRHR
All Species:
8.79
Human Site:
S194
Identified Species:
19.33
UniProt:
P30968
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30968
NP_000397.1
328
37731
S194
S
G
Q
T
K
V
F
S
Q
C
V
T
H
C
S
Chimpanzee
Pan troglodytes
XP_526608
328
37738
S194
S
G
Q
T
K
V
F
S
Q
C
V
T
H
C
S
Rhesus Macaque
Macaca mulatta
Q95JG1
379
41441
A196
V
T
K
G
S
F
K
A
R
W
Q
E
T
T
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q01776
327
37665
Q194
S
G
P
T
V
F
S
Q
C
V
T
H
C
S
F
Rat
Rattus norvegicus
P30969
327
37729
Q194
S
G
P
A
V
F
S
Q
C
V
T
H
C
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001116830
332
37290
S198
S
G
K
M
D
T
F
S
Q
C
V
T
H
S
S
Chicken
Gallus gallus
NP_001012627
419
45457
T220
H
N
F
T
Q
C
T
T
H
G
S
F
P
Q
P
Frog
Xenopus laevis
NP_001079176
368
41711
G227
T
R
I
L
W
E
I
G
K
Q
M
K
H
K
N
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
Q196
D
F
N
L
V
V
S
Q
P
G
Q
E
T
Y
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001035354
349
40615
A194
S
Q
C
V
T
F
N
A
F
P
T
Y
T
H
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116990
440
49788
D222
P
S
F
T
Q
C
V
D
Y
N
F
A
N
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
35.6
N.A.
N.A.
89.3
87.5
N.A.
70.4
32.9
38.8
21.1
N.A.
N.A.
30
N.A.
26.1
Protein Similarity:
100
100
50.4
N.A.
N.A.
94.5
93.5
N.A.
81.9
49.1
56.2
39.8
N.A.
N.A.
51.8
N.A.
43.6
P-Site Identity:
100
100
0
N.A.
N.A.
20
13.3
N.A.
66.6
6.6
6.6
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
20
13.3
N.A.
73.3
20
33.3
6.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
19
0
0
0
10
0
0
0
% A
% Cys:
0
0
10
0
0
19
0
0
19
28
0
0
19
19
0
% C
% Asp:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
19
0
0
10
% E
% Phe:
0
10
19
0
0
37
28
0
10
0
10
10
0
0
19
% F
% Gly:
0
46
0
10
0
0
0
10
0
19
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
19
37
10
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
19
0
19
0
10
0
10
0
0
10
0
10
0
% K
% Leu:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
10
0
0
10
0
0
10
10
10
% N
% Pro:
10
0
19
0
0
0
0
0
10
10
0
0
10
0
10
% P
% Gln:
0
10
19
0
19
0
0
28
28
10
19
0
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% R
% Ser:
55
10
0
0
10
0
28
28
0
0
10
0
0
28
28
% S
% Thr:
10
10
0
46
10
10
10
10
0
0
28
28
28
10
0
% T
% Val:
10
0
0
10
28
28
10
0
0
19
28
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _