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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNRHR
All Species:
22.12
Human Site:
S254
Identified Species:
48.67
UniProt:
P30968
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30968
NP_000397.1
328
37731
S254
H
E
L
Q
L
N
Q
S
K
N
N
I
P
R
A
Chimpanzee
Pan troglodytes
XP_526608
328
37738
S254
Y
E
L
Q
L
N
Q
S
K
N
N
I
P
R
A
Rhesus Macaque
Macaca mulatta
Q95JG1
379
41441
S251
G
E
F
A
L
C
R
S
F
D
N
C
P
R
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q01776
327
37665
S253
R
K
L
Q
L
N
Q
S
K
N
N
I
P
R
A
Rat
Rattus norvegicus
P30969
327
37729
S253
R
K
L
Q
L
N
Q
S
K
N
N
I
P
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001116830
332
37290
S258
Q
S
L
E
L
N
R
S
N
N
N
I
P
R
A
Chicken
Gallus gallus
NP_001012627
419
45457
S279
R
D
V
P
L
R
C
S
G
S
N
I
P
R
A
Frog
Xenopus laevis
NP_001079176
368
41711
F295
E
Y
L
N
H
S
L
F
L
F
G
L
L
H
T
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
I254
R
K
R
R
L
L
K
I
I
T
T
L
V
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001035354
349
40615
A254
S
I
G
F
L
T
R
A
K
I
R
T
L
K
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116990
440
49788
G286
H
P
G
L
R
R
T
G
L
D
R
L
P
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
35.6
N.A.
N.A.
89.3
87.5
N.A.
70.4
32.9
38.8
21.1
N.A.
N.A.
30
N.A.
26.1
Protein Similarity:
100
100
50.4
N.A.
N.A.
94.5
93.5
N.A.
81.9
49.1
56.2
39.8
N.A.
N.A.
51.8
N.A.
43.6
P-Site Identity:
100
93.3
40
N.A.
N.A.
86.6
86.6
N.A.
66.6
46.6
6.6
6.6
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
100
53.3
N.A.
N.A.
93.3
93.3
N.A.
80
66.6
20
33.3
N.A.
N.A.
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
64
% A
% Cys:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
10
28
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
0
0
10
10
10
0
0
0
0
0
% F
% Gly:
10
0
19
0
0
0
0
10
10
0
10
0
0
0
0
% G
% His:
19
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
10
10
10
0
55
0
0
0
% I
% Lys:
0
28
0
0
0
0
10
0
46
0
0
0
0
10
0
% K
% Leu:
0
0
55
10
82
10
10
0
19
0
0
28
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
0
46
0
0
10
46
64
0
0
0
0
% N
% Pro:
0
10
0
10
0
0
0
0
0
0
0
0
73
0
0
% P
% Gln:
10
0
0
37
0
0
37
0
0
0
0
0
0
0
0
% Q
% Arg:
37
0
10
10
10
19
28
0
0
0
19
0
0
73
0
% R
% Ser:
10
10
0
0
0
10
0
64
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
10
0
0
10
10
10
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _