KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNRHR
All Species:
13.64
Human Site:
S301
Identified Species:
30
UniProt:
P30968
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30968
NP_000397.1
328
37731
S301
P
E
M
L
N
R
L
S
D
P
V
N
H
F
F
Chimpanzee
Pan troglodytes
XP_526608
328
37738
S301
P
E
M
L
N
R
V
S
D
P
V
N
H
F
F
Rhesus Macaque
Macaca mulatta
Q95JG1
379
41441
P298
P
T
M
L
T
E
V
P
P
S
L
S
H
I
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q01776
327
37665
S300
P
E
M
L
N
R
V
S
E
P
V
N
H
F
F
Rat
Rattus norvegicus
P30969
327
37729
S300
P
E
M
L
N
R
V
S
E
P
V
N
H
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001116830
332
37290
P305
P
E
M
L
N
R
V
P
D
P
V
S
H
F
F
Chicken
Gallus gallus
NP_001012627
419
45457
V326
P
R
A
M
Q
Q
K
V
P
P
S
L
S
H
I
Frog
Xenopus laevis
NP_001079176
368
41711
A342
E
K
N
S
K
Q
L
A
G
S
E
L
N
I
K
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
A301
L
L
L
A
H
P
Y
A
T
C
L
A
Y
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001035354
349
40615
L301
D
Q
R
I
Q
K
G
L
F
L
F
A
C
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116990
440
49788
K333
S
G
W
Q
S
E
E
K
K
M
L
K
P
E
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
35.6
N.A.
N.A.
89.3
87.5
N.A.
70.4
32.9
38.8
21.1
N.A.
N.A.
30
N.A.
26.1
Protein Similarity:
100
100
50.4
N.A.
N.A.
94.5
93.5
N.A.
81.9
49.1
56.2
39.8
N.A.
N.A.
51.8
N.A.
43.6
P-Site Identity:
100
93.3
26.6
N.A.
N.A.
86.6
86.6
N.A.
80
13.3
6.6
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
46.6
N.A.
N.A.
100
100
N.A.
93.3
26.6
33.3
33.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
19
0
0
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% D
% Glu:
10
46
0
0
0
19
10
0
19
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
46
46
% F
% Gly:
0
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
55
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
19
10
% I
% Lys:
0
10
0
0
10
10
10
10
10
0
0
10
0
0
10
% K
% Leu:
10
10
10
55
0
0
19
10
0
10
28
19
0
0
10
% L
% Met:
0
0
55
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
46
0
0
0
0
0
0
37
10
0
19
% N
% Pro:
64
0
0
0
0
10
0
19
19
55
0
0
10
0
0
% P
% Gln:
0
10
0
10
19
19
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
0
46
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
10
0
0
37
0
19
10
19
10
0
0
% S
% Thr:
0
10
0
0
10
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
46
10
0
0
46
0
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _